Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | GAA | P10253 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844878 | 0.85 | KMT2A (0.62) | KMT2AGAAMEN1RAB9ANPC1 | |
| SCHEMBL6681734 | 0.84 | RAB9A (0.63) | KMT2AGAAMEN1RAB9ANPC1 | |
| SCHEMBL6681732 | 0.84 | RAB9A (0.63) | KMT2AGAAMEN1RAB9ANPC1 | |
| SCHEMBL23392916 | 0.78 | NAMPT (0.56) | KMT2AGAAMEN1RAB9ANPC1 | |
| SCHEMBL23392914 | 0.78 | NAMPT (0.56) | KMT2AGAAMEN1RAB9ANPC1 | |
| SCHEMBL8225127 | 0.77 | RAB9A (0.62) | KMT2AGAAMEN1RAB9ANPC1 | |
| SCHEMBL7950232 | 0.77 | RAB9A (0.65) | KMT2AGAAMEN1RAB9ANPC1 | |
| SCHEMBL1605962 | 0.77 | ALDH1A1 (0.68) | KMT2AGAAMEN1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6682861 | 0.76 | KMT2A (0.69) | KMT2AGAAMEN1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6682864 | 0.76 | KMT2A (0.69) | KMT2AGAAMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |