Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681734 | 1.00 | RAB9A (0.63) | RAB9AKMT2AMEN1NPC1GAA | |
| SCHEMBL8225127 | 0.86 | RAB9A (0.62) | RAB9AKMT2AMEN1NPC1GAA | |
| SCHEMBL7950232 | 0.86 | RAB9A (0.65) | RAB9AKMT2AMEN1NPC1GAA | |
| SCHEMBL1605962 | 0.86 | ALDH1A1 (0.68) | RAB9AKMT2AMEN1NPC1GAA | |
| Hydrochloric Acid SCHEMBL1606124 | 0.85 | RAB9A (0.64) | RAB9AKMT2AMEN1NPC1GAA | |
| Hydrochloric Acid SCHEMBL6682861 | 0.85 | KMT2A (0.69) | RAB9AKMT2AMEN1NPC1GAA | |
| Hydrochloric Acid SCHEMBL6682864 | 0.85 | KMT2A (0.69) | RAB9AKMT2AMEN1NPC1GAA | |
| SCHEMBL2790141 | 0.84 | KMT2A (0.67) | RAB9AKMT2AMEN1NPC1GAA | |
| SCHEMBL2844878 | 0.83 | KMT2A (0.62) | RAB9AKMT2AMEN1NPC1GAA | |
| SCHEMBL4413307 | 0.82 | GAA (0.69) | RAB9AKMT2AMEN1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |