Indene

Indene

SCHEMBL27901419

C1=Cc2ccccc2C1.C=Cc1ccccc1.c1ccc2occc2c1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indene SCHEMBL25262 0.87 CA1 (0.40) CYP2D6CYP2C19CA1CA2
Naphthalene SCHEMBL10727204 0.86 ALDH1A1 (0.47) ALDH1A1TSHRCYP2D6CYP2C19CA1
Indene SCHEMBL200671 0.84 ALDH1A1 (0.52) ALDH1A1TSHRCYP2D6CYP2C19CA1
Indene SCHEMBL9444068 0.84 ALDH1A1 (0.52) ALDH1A1TSHRCYP2D6CYP2C19CA1
Indene SCHEMBL29813684 0.84 ALDH1A1 (0.52) ALDH1A1TSHRCYP2D6CYP2C19CA1
Indene SCHEMBL8625326 0.83 ALDH1A1 (0.50) ALDH1A1TSHRCYP2D6CYP2C19CA1
Benzofuran SCHEMBL27366636 0.83 ALDH1A1 (0.54) ALDH1A1TSHRCA1CA2
Coumarin SCHEMBL7526019 0.81 CA12 (0.49) ALDH1A1TSHRCYP2D6CYP2C19CA1
Indene SCHEMBL27535655 0.79 ALDH1A1 (0.45) ALDH1A1TSHRCYP2D6CYP2C19CA1
Indene SCHEMBL3169287 0.77 ALDH1A1 (0.44) ALDH1A1TSHRCYP2D6CYP2C19CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106104322-A Functional membrane, polaroid and display device 柯尼卡美能达株式会社 2016-11-09 CN disclosed
CN-103080616-B Sealing material DAIKIN INDUSTRIES, LTD. (JP) 2016-04-27 CN disclosed
CN-103097794-A Hose DAIKIN IND LTD 2013-05-08 CN disclosed
CN-103080616-A Seal member DAIKIN IND LTD 2013-05-01 CN disclosed