Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27604855 | 0.90 | KIF11 (0.33) | KDM1AKDM1BKCNH2KIF11 | |
| SCHEMBL22527896 | 0.82 | NPC1 (0.38) | KDM1AKDM1BNPC1RAB9AKCNH2 | |
| SCHEMBL2351106 | 0.79 | KDM1A (0.37) | KDM1AKDM1BNPC1RAB9A | |
| SCHEMBL27901473 | 0.74 | CCR5 (0.39) | — | |
| SCHEMBL2530790 | 0.73 | KDM1A (0.39) | KDM1AKDM1BKCNH2 | |
| SCHEMBL2039343 | 0.73 | KDM1A (0.35) | KDM1AKDM1BKCNH2 | |
| SCHEMBL856202 | 0.73 | KDM1A (0.44) | KDM1AKDM1BKCNH2 | |
| SCHEMBL24575335 | 0.73 | KDM1A (0.38) | KDM1AKDM1BNPC1RAB9AKCNH2 | |
| SCHEMBL4314806 | 0.73 | KIF11 (0.36) | KDM1AKDM1BNPC1RAB9AKCNH2 | |
| SCHEMBL16794042 | 0.72 | KDM1A (0.49) | KDM1AKDM1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102844300-A | Cyclic ketoenols for use in therapy | BAYER SCHERING PHARMA AG | 2012-12-26 | — | — | CN | disclosed |