Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314806 | 0.92 | KIF11 (0.36) | KDM1AKDM1BKCNH2RORCKIF11 | |
| SCHEMBL16005219 | 0.86 | DGAT1 (0.36) | KDM1AKDM1BKCNH2RORCKIF11 | |
| SCHEMBL22527896 | 0.86 | NPC1 (0.38) | KDM1AKDM1BKCNH2KIF11NPC1 | |
| SCHEMBL31485520 | 0.85 | CCR6 (0.36) | RORCDGAT1ICMT | |
| SCHEMBL30886492 | 0.85 | KIF11 (0.34) | KDM1AKDM1BKCNH2RORCKIF11 | |
| SCHEMBL27604855 | 0.84 | KIF11 (0.33) | KDM1AKDM1BKCNH2RORCKIF11 | |
| SCHEMBL29819673 | 0.84 | HDAC1 (0.40) | RORCICMTHDAC1HDAC8HTT | |
| SCHEMBL12984764 | 0.84 | HDAC1 (0.40) | RORCICMTHDAC1HDAC8HTT | |
| SCHEMBL7466464 | 0.82 | CXCL8 (0.39) | KDM1AKDM1BKCNH2NPC1RAB9A | |
| SCHEMBL30886409 | 0.79 | TDO2 (0.39) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4269399-A1 | FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022135572-A1 | FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF | 四川海思科制药有限公司 | 2022-06-30 | — | — | WO | disclosed |