Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2067420 | 0.74 | LMNA (0.46) | LMNA | |
| SCHEMBL2068376 | 0.73 | — | — | |
| SCHEMBL2067121 | 0.73 | LMNA (0.33) | LMNA | |
| SCHEMBL2068955 | 0.70 | KDM4E (0.32) | LMNA | |
| SCHEMBL2067562 | 0.68 | ALDH1A1 (0.46) | LMNA | |
| SCHEMBL791750 | 0.66 | — | — | |
| SCHEMBL17652390 | 0.62 | KDM4E (0.35) | LMNA | |
| SCHEMBL2068436 | 0.62 | KDM4E (0.30) | — | |
| SCHEMBL27310576 | 0.62 | ADRA1A (0.33) | — | |
| SCHEMBL2067580 | 0.61 | NISCH (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803259-A | 1H-Imidazo[4, 5-c]quinolinone compounds, useful for the treatment of proliferative diseases | NOVARTIS AG | 2012-11-28 | — | — | CN | disclosed |