Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 6/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27919502 | 0.88 | CYP11B2 (0.36) | CYP11B2CYP17A1RBP4C5AR1HTR2A | |
| SCHEMBL27901787 | 0.84 | CYP11B2 (0.35) | CYP11B2CYP17A1SCDCYP11B1 | |
| SCHEMBL27919520 | 0.84 | HTR2C (0.43) | CYP11B2CYP17A1RBP4HTR2AHTR2C | |
| SCHEMBL27919506 | 0.83 | CYP17A1 (0.45) | CYP17A1 | |
| SCHEMBL27901758 | 0.83 | HTR2A (0.39) | CYP11B2TRPM8CYP17A1SCDHTR2A | |
| SCHEMBL27919510 | 0.81 | CYP11B2 (0.35) | CYP11B2CYP17A1C5AR1HTR2AHTR2C | |
| SCHEMBL27919589 | 0.81 | CYP11B2 (0.33) | CYP11B2TRPM8C5AR1 | |
| SCHEMBL27919566 | 0.80 | CYP11B2 (0.33) | CYP11B2TRPM8RBP4C5AR1HTR2A | |
| SCHEMBL27919635 | 0.78 | SIRT6 (0.36) | CYP11B2C5AR1HTR2AHTR2C | |
| SCHEMBL27901761 | 0.77 | HTR2C (0.39) | CYP11B2TRPM8CYP17A1SCDCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103108871-A | 17a-hydroxylase/c17,20-lyase inhibitors | NOVARTIS AG | 2013-05-15 | — | — | CN | disclosed |