Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 5/20 | 0.38 |
| ▸ | THRA | P10827 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3601655 | 0.85 | THRB (0.51) | THRBTHRABCHEACHEKDM4E | |
| SCHEMBL3598090 | 0.83 | BCHE (0.45) | THRBTHRABCHEACHEKDM4E | |
| SCHEMBL3600323 | 0.81 | BCHE (0.43) | THRBTHRABCHEACHERXRA | |
| SCHEMBL27639101 | 0.80 | CFD (0.40) | THRBTHRABCHEACHEKDM4E | |
| SCHEMBL27639120 | 0.80 | ADRB3 (0.46) | THRBTHRABCHEACHEALDH1A1 | |
| SCHEMBL4820263 | 0.80 | SMN1; SMN2 (0.44) | KEAP1NFE2L2THRBTHRABCHE | |
| SCHEMBL3590188 | 0.79 | BCHE (0.42) | THRBTHRABCHEACHERXRA | |
| SCHEMBL3593921 | 0.79 | PPARA (0.45) | THRBTHRA | |
| SCHEMBL27639102 | 0.78 | BCHE (0.37) | THRBTHRABCHEACHERXRA | |
| SCHEMBL3594435 | 0.78 | SLC5A1 (0.42) | BCHEACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1816536-B | Cannabinoid receptor modulators | TAKAEDA CHEMICAL IND LTD | 2012-12-26 | — | — | CN | disclosed |