SCHEMBL4820263

SCHEMBL4820263

CCC(Oc1cc(C)cc(C)c1Cc1ccc(C(C)C)cc1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.44
PPARA Q07869 4/20 0.41
BCHE P06276 4/20 0.38
ACHE P22303 4/20 0.38
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
SAE1 Q9UBE0 1/20 0.37
UBA2 Q9UBT2 1/20 0.37
THRB P10828 5/20 0.37
THRA P10827 4/20 0.37
PTGDR2 Q9Y5Y4 2/20 0.36
PPARG P37231 3/20 0.36
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27902001 0.80 KEAP1 (0.39) BCHEACHEKDM4EMAPTSAE1
SCHEMBL3601655 0.80 THRB (0.51) BCHEACHEKDM4ETHRBTHRA
SCHEMBL27639101 0.79 CFD (0.40) BCHEACHEKDM4EMAPTSAE1
SCHEMBL3600323 0.78 BCHE (0.43) BCHEACHETHRBTHRA
SCHEMBL3593921 0.78 PPARA (0.45) PPARATHRBTHRAPPARG
SCHEMBL27639102 0.77 BCHE (0.37) BCHEACHEKDM4EMAPTSAE1
SCHEMBL3598090 0.77 BCHE (0.45) BCHEACHEKDM4ETHRBTHRA
SCHEMBL3594435 0.77 SLC5A1 (0.42) BCHEACHE
SCHEMBL27639121 0.77 ALOX15 (0.39) BCHEACHEKDM4EMAPTSAE1
SCHEMBL27639120 0.77 ADRB3 (0.46) BCHEACHETHRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7465815-B2 Cannabinoid receptor modulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-12-16 US disclosed
US-20070099990-A1 Cannabinoid receptor modulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070099990-A1 Cannabinoid receptor modulator CNR1, CNR2, GPR18 SMN1; SMN2 4180/4885PPARA 490/4885BCHE 2613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.