Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | VHL | P40337 | 1/20 | 0.35 |
| ▸ | ELOC | Q15369 | 1/20 | 0.35 |
| ▸ | ELOB | Q15370 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520033 | 0.78 | TSHR (0.42) | TSHRHPGDHDAC8HDAC2PRSS1 | |
| SCHEMBL8670278 | 0.78 | PRSS1 (0.43) | TSHRHPGDHDAC8HDAC2PRSS1 | |
| SCHEMBL1124751 | 0.75 | ALDH5A1 (0.52) | TSHRHPGDHDAC8HDAC2CA12 | |
| SCHEMBL6937222 | 0.74 | HDAC8 (0.53) | TSHRHPGDHDAC8HDAC2PRSS1 | |
| SCHEMBL6937219 | 0.74 | HDAC8 (0.53) | TSHRHPGDHDAC8HDAC2PRSS1 | |
| SCHEMBL41775 | 0.72 | TSHR (0.67) | TSHRHPGDPRSS1PRSS2PRSS3 | |
| SCHEMBL24197429 | 0.71 | HDAC8 (0.56) | TSHRHPGDHDAC8HDAC2CA12 | |
| SCHEMBL9516832 | 0.71 | TSHR (0.40) | TSHRHPGDHDAC8HDAC2PRSS1 | |
| SCHEMBL8669661 | 0.71 | TSHR (0.58) | TSHRHPGDHDAC8HDAC2PRSS1 | |
| SCHEMBL506795 | 0.71 | TSHR (0.50) | TSHRHPGDHDAC8HDAC2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102844318-A | Compounds for treating respiratory syncytial virus infections | BIOTA SCIENT MAN | 2012-12-26 | — | — | CN | disclosed |