Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | VHL | P40337 | 1/20 | 0.37 |
| ▸ | ELOC | Q15369 | 1/20 | 0.37 |
| ▸ | ELOB | Q15370 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186171 | 0.81 | ALDH1A1 (0.42) | HPGDALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8670278 | 0.80 | PRSS1 (0.43) | TSHRHPGDHDAC8HDAC2NOS3 | |
| SCHEMBL4661736 | 0.79 | HDAC8 (0.44) | TSHRHPGDHDAC8HDAC2NOS3 | |
| SCHEMBL4661738 | 0.79 | HDAC8 (0.44) | TSHRHPGDHDAC8HDAC2NOS3 | |
| SCHEMBL1612299 | 0.79 | ALDH1A1 (0.48) | TSHRHPGDCA2ALOX5PTGS1 | |
| SCHEMBL27902002 | 0.78 | TSHR (0.40) | TSHRHPGDHDAC8HDAC2NOS3 | |
| SCHEMBL3240509 | 0.77 | TSHR (0.43) | TSHRHPGDHDAC8HDAC2NOS3 | |
| SCHEMBL1124751 | 0.77 | ALDH5A1 (0.52) | TSHRHPGDHDAC8HDAC2CA12 | |
| Alcohol SCHEMBL5686049 | 0.76 | ALDH1A1 (0.50) | TSHRHPGDHDAC8HDAC2NOS3 | |
| SCHEMBL6937222 | 0.76 | HDAC8 (0.53) | TSHRHPGDHDAC8HDAC2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179529-A1 | NOVEL HYDROXAMIC ACID DERIVATIVES | Daiichi Fine Chemical Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-1101492-A1 | NOVEL REMEDIES FOR ALLERGIC DISEASES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |