Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | VHL | P40337 | 1/20 | 0.42 |
| ▸ | ELOC | Q15369 | 1/20 | 0.42 |
| ▸ | ELOB | Q15370 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41775 | 0.83 | TSHR (0.67) | TSHRPRSS1PRSS2PRSS3VHL | |
| SCHEMBL131361 | 0.83 | ALDH1A1 (0.67) | TSHRTRPA1ALDH1A1CES2CES1 | |
| SCHEMBL11432442 | 0.82 | MAOB (0.44) | TSHRMKNK1MKNK2KIF11HDAC2 | |
| SCHEMBL1109793 | 0.77 | CA2 (0.59) | TSHRTRPA1ALDH1A1CES2CES1 | |
| SCHEMBL5497046 | 0.77 | TSHR (0.46) | TSHRTRPA1ALDH1A1CES2CES1 | |
| SCHEMBL1919140 | 0.77 | TDP1 (0.55) | TSHRALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL31672218 | 0.76 | TSHR (0.59) | TSHRPRSS1PRSS2PRSS3VHL | |
| SCHEMBL1229742 | 0.75 | ACHE (0.48) | TSHRTRPA1ALDH1A1CES2CES1 | |
| SCHEMBL883392 | 0.75 | — | — | |
| SCHEMBL104349 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121197436-B | Drug-loaded micelle capable of effectively crossing blood brain barrier as well as preparation method and application thereof | 湖北大学 | 2026-05-19 | — | — | CN | claimed |
| CN-119823515-B | Preparation method of wear-resistant modified nylon plastic | 昆山新普发塑料有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-115959962-B | Visible light-promoted halogenated alkane hydrodehalogenation method | 中国科学院兰州化学物理研究所 | 2025-05-23 | — | — | CN | claimed |
| CN-119912927-A | Corrosion inhibitor for oilfield acidification and preparation method thereof | 东营江源化工有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119823515-A | Preparation method of wear-resistant modified nylon plastic | 昆山新普发塑料有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119798180-A | Curing agent and preparation method thereof, concrete surface protective agent and preparation method thereof, and concrete | 广东长大工程检测有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-119708451-A | Preparation method of polylactic acid antibacterial material for medical stent | 湘南学院附属医院 | 2025-03-28 | — | — | CN | claimed |
| CN-119614188-A | Multicolor fluorescence emission lignin-based carbon dot and preparation method and application thereof | 华南理工大学 | 2025-03-14 | — | — | CN | claimed |
| CN-118755367-B | Modified maleimide-containing fire-resistant water-based paint and preparation method thereof | 隽秀新材料科技(苏州)有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-118755367-A | Modified maleimide-containing fire-resistant water-based paint and preparation method thereof | 隽秀新材料科技(苏州)有限公司 | 2024-10-11 | — | — | CN | claimed |
| US-20220088202-A1 | Nucleic Acid-Drug Conjugate, Drug Delivery System, Preparation Method Therefor and Use Thereof | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2022-03-24 | — | — | US | claimed |
| CN-109568595-B | Nucleic acid-drug conjugates, drug delivery systems, methods of making and uses thereof | 上海交通大学 | 2022-01-25 | — | — | CN | claimed |
| CN-112210049-A | Water reducing agent suitable for high content of sandstone soil and preparation method thereof | 梁剑 | 2021-01-12 | — | — | CN | claimed |
| CN-109568595-A | Nucleic acid-drug conjugates, drug delivery system and its preparation method and application | 上海交通大学 | 2019-04-05 | — | — | CN | claimed |
| US-20100121057-A1 | Process for the Preparation of Piperazine Benzothiazoles | MERCK SERONO SA (CH) | 2010-05-13 | — | — | US | claimed |
| EP-2137173-A2 | PROCESS FOR THE PREPARATION OF PIPERAZINE BENZOTHIAZOLES | Laboratoires Serono SA (CH) | 2009-12-30 | — | — | EP | claimed |
| WO-2008125518-A2 | PROCESS FOR THE PREPARATION OF PIPERAZINE BENZOTHIAZOLES | MERCK SERONO S.A. (CH) | 2008-10-23 | — | — | WO | claimed |
| CN-121197436-B | Drug-loaded micelle capable of effectively crossing blood brain barrier as well as preparation method and application thereof | 湖北大学 | 2026-05-19 | — | — | CN | disclosed |
| WO-1989007100-A1 | 2,2-DISUBSTITUTED GLYCEROL AND GLYCEROL-LIKE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1989-08-10 | — | — | WO | disclosed |
| WO-1989007099-A1 | 2,2-DISUBSTITUTED GLYCEROL AND GLYCEROL-LIKE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1989-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121057-A1 | Process for the Preparation of Piperazine Benzothiazoles | NUDT1, BRD1, BRD4 | TSHR 3268/4885TRPA1 3625/4885ALDH1A1 403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.