Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27532645 | 0.85 | SMYD3 (0.39) | SMYD3NAMPTALOX15SMN1; SMN2GAA | |
| SCHEMBL28174741 | 0.81 | SMN1; SMN2 (0.41) | ALOX15HIF1AESR1SMN1; SMN2KMT2A | |
| SCHEMBL27368413 | 0.76 | HPGD (0.37) | SMYD3NAMPTHPGD | |
| SCHEMBL29284873 | 0.74 | CA2 (0.34) | ALOX15HIF1AESR1SMN1; SMN2KMT2A | |
| SCHEMBL27554350 | 0.74 | HPGD (0.34) | SMYD3NAMPTHPGD | |
| SCHEMBL27517113 | 0.73 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL6265235 | 0.70 | POLB (0.40) | SMN1; SMN2KMT2AGAAALDH1A1POLB | |
| SCHEMBL343503 | 0.69 | GRN (0.53) | SMYD3NAMPTKMT2AKCNT1POLB | |
| SCHEMBL12646244 | 0.69 | SMYD3 (0.51) | SMYD3NAMPTKMT2AHPGDALDH1A1 | |
| SCHEMBL9199202 | 0.69 | SMYD3 (0.51) | SMYD3NAMPTSMN1; SMN2KMT2AKCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187894-A | The preparation method of 1 methyl 3 ethyl 4 chlorine 5 pyrazole carboxylic acid ethyl ester | 潍坊鑫诺化工有限公司 | 2016-12-07 | — | — | CN | claimed |
| CN-103556174-A | Synthesis method of ethyl 4-chloro-1-methyl-3-ethyl-5-pyrazolylcarboxylate | UNIV HARBIN SCIENCE & TECH | 2014-02-05 | — | — | CN | claimed |
| CN-103508959-A | Synthesis method of 1-methyl-3-ethyl-5-pyrazolyl ethyl carboxylate | UNIV HARBIN SCIENCE & TECH | 2014-01-15 | — | — | CN | claimed |
| CN-103102307-A | Method for synthesizing tolfenpyrad | UNIV HEILONGJIANG | 2013-05-15 | — | — | CN | claimed |
| CN-106187894-A | The preparation method of 1 methyl 3 ethyl 4 chlorine 5 pyrazole carboxylic acid ethyl ester | 潍坊鑫诺化工有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-103556174-A | Synthesis method of ethyl 4-chloro-1-methyl-3-ethyl-5-pyrazolylcarboxylate | UNIV HARBIN SCIENCE & TECH | 2014-02-05 | — | — | CN | disclosed |
| CN-103508959-A | Synthesis method of 1-methyl-3-ethyl-5-pyrazolyl ethyl carboxylate | UNIV HARBIN SCIENCE & TECH | 2014-01-15 | — | — | CN | disclosed |
| CN-103508959-A | Synthesis method of 1-methyl-3-ethyl-5-pyrazolyl ethyl carboxylate | UNIV HARBIN SCIENCE & TECH | 2014-01-15 | — | — | CN | disclosed |
| CN-103508959-A | Synthesis method of 1-methyl-3-ethyl-5-pyrazolyl ethyl carboxylate | UNIV HARBIN SCIENCE & TECH | 2014-01-15 | — | — | CN | disclosed |
| CN-103102307-A | Method for synthesizing tolfenpyrad | UNIV HEILONGJIANG | 2013-05-15 | — | — | CN | disclosed |