Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6630242 | 0.90 | POLB (0.36) | POLBALOX5HTTCA2SMN1; SMN2 | |
| SCHEMBL7102276 | 0.85 | ALOX5 (0.37) | POLBALOX5HTTCA2GAA | |
| SCHEMBL859 | 0.76 | POLB (0.50) | POLBSMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL6263848 | 0.73 | ALOX5 (0.37) | POLBALOX5SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27902151 | 0.70 | SMYD3 (0.39) | POLBSMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL6360335 | 0.70 | POLB (0.42) | POLBSMN1; SMN2LMNASOAT1TSHR | |
| SCHEMBL6630708 | 0.69 | ALOX5 (0.38) | POLBALOX5CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL20503314 | 0.69 | LMNA (0.44) | POLBSMN1; SMN2LMNACYP4F2CYP4A11 | |
| SCHEMBL13995818 | 0.68 | POLB (0.51) | POLBGAAALDH1A1LMNAGFER | |
| SCHEMBL9965045 | 0.68 | BCHE (0.49) | POLBHTTSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104406-B1 | METHOD FOR PREPARING 1-ALKYL-PYRAZOL-5-CARBOXYLIC ACID ESTERS III | LANXESS DEUTSCHLAND GMBH (DE) | 2005-11-23 | — | — | EP | disclosed |
| EP-1091940-B1 | METHOD FOR PREPARING 1-ALKYL-PYRAZOL-5-CARBOXYLIC ACID ESTERS | BAYER AG (DE) | 2003-09-10 | — | — | EP | disclosed |
| EP-0854142-B1 | Process for the preparation of 1-alkylpyrazole-5-carboxylic esters | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| EP-1104406-A1 | METHOD FOR PREPARING 1-ALKYL-PYRAZOL-5-CARBOXYLIC ACID ESTERS III | Bayer Aktiengesellschaft (DE) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000010978-A1 | METHOD FOR PREPARING 1-ALKYL-PYRAZOL-5-CARBOXYLIC ACID ESTERS III | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-02 | — | — | WO | disclosed |
| EP-0854142-A1 | Process for the preparation of 1-alkylpyrazole-5-carboxylic esters | BAYER AG (DE) | 1998-07-22 | — | — | EP | disclosed |