Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962481 | 0.82 | TTR (0.36) | TTRALBMEN1KMT2AGABRA1 | |
| SCHEMBL24337481 | 0.79 | TTR (0.38) | TTRALBMEN1KMT2AGABRA1 | |
| SCHEMBL27851618 | 0.78 | CNR1 (0.36) | — | |
| SCHEMBL27868545 | 0.78 | GRM5 (0.36) | PGR | |
| SCHEMBL18093834 | 0.78 | GABRA1 (0.39) | GABRA1GABRB1 | |
| SCHEMBL31668166 | 0.78 | GABRA1 (0.39) | GABRA1GABRB1 | |
| SCHEMBL2058684 | 0.76 | GSK3B (0.47) | GSK3BGLA | |
| SCHEMBL30583585 | 0.76 | GSK3B (0.47) | GSK3BGLA | |
| SCHEMBL28002676 | 0.76 | MEN1 (0.34) | TTRALBMEN1KMT2AGSK3B | |
| SCHEMBL200313 | 0.75 | TTR (0.52) | TTRALBMEN1KMT2APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103380133-A | Compounds and their use as BACE inhibitors | ASTRAZENECA AB | 2013-10-30 | — | — | CN | disclosed |
| CN-102858760-A | Glycine chroman-6-sulfonamides for use as inhibitors of diacylglycerol lipase | BRISTOL MYERS SQUIBB CO | 2013-01-02 | — | — | CN | disclosed |