SCHEMBL200313

SCHEMBL200313

N#Cc1cc(Br)cc(Br)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.52
ALB P02768 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
MAOB P27338 3/20 0.41
MAOA P21397 2/20 0.41
HTT P42858 1/20 0.38
VCAM1 P19320 2/20 0.37
TSHR P16473 1/20 0.36
PGR P06401 1/20 0.35
ALDH1A1 P00352 1/20 0.33
CYP2A6 P11509 1/20 0.33
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33
CA6 P23280 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
GPR35 Q9HC97 2/20 0.32
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL504640 0.94 TTR (0.52) TTRALBMEN1KMT2AMAOB
SCHEMBL16950941 0.84 TTR (0.44) TTRALBMEN1KMT2AMAOB
SCHEMBL19062532 0.84 TTR (0.44) TTRALBMEN1KMT2AMAOB
SCHEMBL30345274 0.82 TTR (0.43) TTRALBMEN1KMT2AMAOB
SCHEMBL12514204 0.82 TTR (0.43) TTRALBMEN1KMT2AMAOB
SCHEMBL29451065 0.82 TTR (0.54) TTRALBMEN1KMT2AMAOB
SCHEMBL1883717 0.82 TTR (0.54) TTRALBMEN1KMT2AMAOB
SCHEMBL16951758 0.82 TTR (0.43) TTRALBMEN1KMT2AMAOB
SCHEMBL505159 0.82 MEN1 (0.43) TTRALBMEN1KMT2AMAOB
SCHEMBL254589 0.82 TTR (0.43) TTRALBMEN1KMT2AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 351 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080402-A Hard carbon porous material of tertiary amination triazine polymer, preparation method thereof and negative electrode 2026-05-26 CN claimed
CN-117700728-B Covalent triazine frame polymer based on ullmann reaction, and preparation method and application thereof 宁德师范学院 2024-11-12 CN claimed
CN-114409571-B Synthesis method of nitrile compound 重庆医科大学 2023-05-12 CN claimed
CN-114671854-B High-solubility electron acceptor material and preparation method and application thereof 电子科技大学 2023-04-28 CN claimed
CN-115974843-A Nitrogen heterocyclic ring-based exciplex receptor material and preparation method and application thereof 电子科技大学 2023-04-18 CN claimed
CN-114671854-A High-solubility electron acceptor material and preparation method and application thereof 电子科技大学 2022-06-28 CN claimed
CN-114409571-A Method for synthesizing nitrile compound 重庆医科大学 2022-04-29 CN claimed
CN-109851559-B Nickel metal organic framework material based on double-end pyrazole ligand, and preparation method and application thereof 北京工业大学 2020-11-06 CN claimed
CN-122080402-A Hard carbon porous material of tertiary amination triazine polymer, preparation method thereof and negative electrode 2026-05-26 CN disclosed
CN-122080402-A Hard carbon porous material of tertiary amination triazine polymer, preparation method thereof and negative electrode 2026-05-26 CN disclosed
US-12610949-B2 Heteroaryl-triazole compounds as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2026-04-28 US disclosed
US-20250326780-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2025-10-23 US disclosed
US-20250304567-A1 PYRROLIDIONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE JANSSEN PHARMACEUTICA NV (BE) 2025-10-02 US disclosed
US-12428397-B2 Factor XI activation inhibitors MERCK SHARP & DOHME LLC (US) 2025-09-30 US disclosed
EP-0252564-B1 PROCESS FOR THE PREPARATION OF DIFLUOROBENZAMIDE SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-04-14 EP disclosed
US-5192758-A Antibiotics MERCK & CO., INC. (US) 1993-03-09 US disclosed
US-4968769-A THERMOPLASTICS HAVING DIMENSIONAL STABILITY AT ELEVATED TEMPERATURES SHELL OIL COMPANY (US) 1990-11-06 US disclosed
EP-0372656-A2 Polymers comprising spirolactam units SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-06-13 EP disclosed
CN-87104545-A Preparation method of difluorobenzamide 1988-04-27 CN disclosed
EP-0252564-A2 Process for the preparation of difluorobenzamide SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12610949-B2 Heteroaryl-triazole compounds as pesticides CTRL, PTMS, DDT TTR 1446/4885ALB 2123/4885MEN1 4381/4885
US-20250304567-A1 PYRROLIDIONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE NFKBIA, IKBKG, IKBKB TTR 3601/4885ALB 4271/4885MEN1 4030/4885
US-12428397-B2 Factor XI activation inhibitors F11, TFPI, F13B TTR 1820/4885ALB 2626/4885MEN1 1431/4885
US-20250326780-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME LEF1, GPX1, OCIAD1 TTR 2357/4885ALB 2687/4885MEN1 143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.