Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27886701 | 0.98 | DRD3 (0.38) | DRD3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL19223389 | 0.94 | GPR84 (0.41) | DRD3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL20007764 | 0.86 | CHRM1 (0.42) | DRD3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL15710769 | 0.84 | SIGMAR1 (0.42) | DRD3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL15711008 | 0.83 | SIGMAR1 (0.41) | DRD3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL15711065 | 0.80 | TDP1 (0.45) | TDP1MAPK1MAPTDRD2 | |
| SCHEMBL27914221 | 0.79 | FOLH1 (0.47) | DRD3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL17102940 | 0.78 | SIGMAR1 (0.50) | CHRM1CHRM3GPR84FFAR1KDM5A | |
| SCHEMBL30714400 | 0.77 | GPR84 (0.47) | GPR84FFAR1KDM5AMAPTLCK | |
| SCHEMBL1131461 | 0.77 | GPR84 (0.47) | GPR84FFAR1KDM5AMAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103732601-B | The one class treatment platinum compounds of cell proliferation disorders, its preparation method and application | 北京市丰硕维康技术开发有限责任公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-102863474-A | Platinum compounds for treating cell proliferative diseases and preparation method and application thereof | CHEN XIAOPING | 2013-01-09 | — | — | CN | disclosed |