Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27903555 | 0.86 | DRD3 (0.39) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL27886701 | 0.85 | DRD3 (0.38) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL19223389 | 0.85 | GPR84 (0.41) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL15515280 | 0.83 | CHRM1 (0.39) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Bicarbonate SCHEMBL5875239 | 0.79 | CA12 (0.50) | ADRA1ADRD3SLC6A3HDAC1HDAC2 | |
| Bicarbonate SCHEMBL5875232 | 0.79 | CA12 (0.50) | ADRA1ADRD3SLC6A3HDAC1HDAC2 | |
| SCHEMBL15710731 | 0.79 | TDP1 (0.40) | TDP1CA2CA12CA9MAPK1 | |
| Methylmalonic Acid SCHEMBL5874817 | 0.78 | CA12 (0.41) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Cadaverine Tartrate SCHEMBL5874575 | 0.78 | TSHR (0.50) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Lactic Acid SCHEMBL21145132 | 0.78 | TP53 (0.55) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2740738-B1 | PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASE, PREPARATION METHODS AND USES THEREOF | BEIJING FSWELCOME TECH DEVELOPMENT CO LTD (CN) | 2018-03-28 | — | — | EP | disclosed |