Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27922416 | 0.78 | CYP1A2 (0.37) | GAARAB9ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL12334814 | 0.77 | CRHBP (0.46) | MTNR1AMTNR1BCRHBPCRHR2GAA | |
| SCHEMBL2378380 | 0.77 | MTNR1A (0.48) | MTNR1AMTNR1BPARP1ALDH1A1L3MBTL1 | |
| SCHEMBL2377323 | 0.76 | MTNR1A (0.40) | MTNR1AMTNR1BCRHBPCRHR2GAA | |
| SCHEMBL27641822 | 0.75 | MTNR1A (0.49) | MTNR1AMTNR1BCRHBPCRHR2GAA | |
| SCHEMBL28980326 | 0.75 | MTNR1A (0.47) | MTNR1AMTNR1BGAARAB9ASMN1; SMN2 | |
| SCHEMBL10398568 | 0.75 | CRHBP (0.65) | MTNR1AMTNR1BCRHBPCRHR2GAA | |
| SCHEMBL27533546 | 0.75 | MTNR1A (0.47) | MTNR1AMTNR1BGAARAB9ASMN1; SMN2 | |
| SCHEMBL1400933 | 0.73 | MTNR1A (0.48) | MTNR1AMTNR1BCRHBPCRHR2PARP1 | |
| SCHEMBL2083223 | 0.72 | MTNR1A (0.48) | MTNR1AMTNR1BGAARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103087105-B | Chiral phosphine ligand and comprise the metal catalyst of this part and their application | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-08-05 | — | — | CN | disclosed |
| CN-103087105-A | Chiral phosphine ligand and metal catalyst comprising same and application of chiral phosphine ligand and metal catalyst | SHANGHAI INST ORGANIC CHEM | 2013-05-08 | — | — | CN | disclosed |