Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27641818 | 0.81 | CES2 (0.45) | PARP1CRHBPCRHR2ALDH1A1GAA | |
| SCHEMBL27831317 | 0.79 | ALDH1A1 (0.53) | PARP1CRHBPCRHR2ALDH1A1GAA | |
| SCHEMBL2378380 | 0.79 | MTNR1A (0.48) | MTNR1AMTNR1BPARP1ALDH1A1L3MBTL1 | |
| SCHEMBL28760865 | 0.78 | HTR3E (0.46) | PARP1ALDH1A1GAAL3MBTL1MEN1 | |
| SCHEMBL28980326 | 0.78 | MTNR1A (0.47) | MTNR1AMTNR1BPARP1ALDH1A1GAA | |
| SCHEMBL27662346 | 0.76 | CYP1A2 (0.39) | ALDH1A1LMNAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1635424 | 0.76 | NPSR1 (0.46) | MTNR1AMTNR1BCRHBPCRHR2ALDH1A1 | |
| SCHEMBL2083223 | 0.75 | MTNR1A (0.48) | MTNR1AMTNR1BPARP1ALDH1A1GAA | |
| SCHEMBL27662593 | 0.75 | MTNR1A (0.54) | MTNR1AMTNR1BPARP1MEN1KMT2A | |
| SCHEMBL27904469 | 0.75 | MTNR1A (0.44) | MTNR1AMTNR1BPARP1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101270097-B | Process for production of 1-aryl-5-(trifluoromethyl)-1H-tetrazoles | TOYO BOSEKI | 2011-04-13 | — | — | CN | disclosed |
| CN-100424069-C | Preparation method of N-aryl-2, 2, 2-trifluoro acetimidoyl chloride | TOYO KASEI KOGYO CO LTD (JP) | 2008-10-08 | — | — | CN | disclosed |
| CN-101270097-A | Process for production of 1-aryl-5-(trifluoromethyl)-1H-tetrazoles | TOYO KASEI KOGYO CO LTD (JP) | 2008-09-24 | — | — | CN | disclosed |
| CN-1863765-A | Preparation method of 1-aryl-5- (trifluoromethyl) -1H-tetrazole | TOYO KASEI KOGYO CO LTD (JP) | 2006-11-15 | — | — | CN | disclosed |