Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 5/20 | 0.33 |
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2808828 | 1.00 | HSPA5 (0.42) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL12889972 | 0.89 | EGFR (0.36) | HSPA5CYP2C9CYP2C19HIF1ACYP2D6 | |
| SCHEMBL2785061 | 0.89 | EGFR (0.36) | HSPA5CYP2C9CYP2C19HIF1ACYP2D6 | |
| SCHEMBL14468912 | 0.87 | HSPA5 (0.40) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL2807290 | 0.85 | GSR (0.40) | CYP2C9CYP2C19HIF1AHSD17B10CYP2D6 | |
| SCHEMBL12890012 | 0.85 | GSR (0.40) | CYP2C9CYP2C19HIF1AHSD17B10CYP2D6 | |
| SCHEMBL2788436 | 0.85 | GSR (0.40) | CYP2C9CYP2C19HIF1AHSD17B10CYP2D6 | |
| SCHEMBL2788958 | 0.84 | SCN2A (0.35) | CYP2C9CYP2C19HSD17B10EGFRALDH1A1 | |
| SCHEMBL16374471 | 0.83 | EGFR (0.36) | HSD17B10EGFRALDH1A1POLBMAOB | |
| SCHEMBL12889988 | 0.83 | EGFR (0.36) | HSD17B10EGFRALDH1A1POLBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9523060-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2016-12-20 | — | — | US | disclosed |
| US-9388120-B2 | Nitrogen and hindered phenol containing dual functional macromolecular antioxidants: synthesis, performances and applications | POLNOX CORPORATION (US) | 2016-07-12 | — | — | US | disclosed |
| US-20150159109-A1 | Lubricant Oil Compositions | POLNOX CORPORATION | 2015-06-11 | — | — | US | disclosed |
| US-8927472-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2015-01-06 | — | — | US | disclosed |
| US-20140316163-A1 | NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS | POLNOX CORPORATION (US) | 2014-10-23 | — | — | US | disclosed |
| US-20130130955-A1 | LUBRICANT OIL COMPOSITIONS | POLNOX CORPORATION (US) | 2013-05-23 | — | — | US | disclosed |
| US-20120142968-A1 | Nitrogen and Hindered Phenol Containing Dual Functional Macromolecular Antioxidants: Synthesis, Performances and Applications | POLNOX CORPORATION (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120004150-A1 | Lubricant Oil Compositions | POLNOX CORPORATION | 2012-01-05 | — | — | US | disclosed |
| US-8080689-B2 | Nitrogen and hindered phenol containing dual functional macromolecular antioxidants: synthesis, performances and applications | POLNOX CORPORATION (US) | 2011-12-20 | — | — | US | disclosed |
| US-7799948-B2 | stabilizers for inhibiting oxidation in organic materials, lubricants and petroleum based products, plastics and elastomers, cosmetics, foods and cooking oils | POLNOX CORPORATION (US) | 2010-09-21 | — | — | US | disclosed |
| US-7705075-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2010-04-27 | — | — | US | disclosed |
| US-7705075-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2010-04-27 | — | — | US | disclosed |
| US-20080293856-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2008-11-27 | — | — | US | disclosed |
| US-20080293856-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2008-11-27 | — | — | US | disclosed |
| US-20070161522-A1 | Lubricant oil compositions | POLNOX CORPORATION | 2007-07-12 | — | — | US | disclosed |
| US-20070161522-A1 | Lubricant oil compositions | POLNOX CORPORATION | 2007-07-12 | — | — | US | disclosed |
| US-20070149660-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2007-06-28 | — | — | US | disclosed |
| US-20070149660-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2007-06-28 | — | — | US | disclosed |
| WO-2007064843-A1 | LUBRICANT OIL COMPOSITIONS | POLNOX CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007050991-A1 | STABILIZED POLYOLEFIN COMPOSITIONS | POLNOX CORPORATION (US) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140316163-A1 | NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS | CAT, LPO, DUOX1 | HSPA5 940/4885CYP2C9 1264/4885CYP2C19 1530/4885 |
| US-20120142968-A1 | Nitrogen and Hindered Phenol Containing Dual Functional Macromolecular Antioxidants: Synthesis, Performances and Applications | CAT, LPO, DUOX1 | HSPA5 940/4885CYP2C9 1264/4885CYP2C19 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.