SCHEMBL2807290

SCHEMBL2807290

CC(Cc1ccc(Nc2ccc(NCc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)cc2)cc1)CC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.40
HMGCR P04035 2/20 0.36
FFAR1 O14842 1/20 0.35
SCN2A Q99250 2/20 0.35
GAA P10253 6/20 0.35
ALDH1A1 P00352 6/20 0.35
TSHR P16473 3/20 0.35
LMNA P02545 2/20 0.35
MEN1 O00255 5/20 0.34
KMT2A Q03164 5/20 0.34
EGFR P00533 2/20 0.34
ALOX15 P16050 4/20 0.34
MAPK1 P28482 4/20 0.34
BLM P54132 4/20 0.34
MAPT P10636 4/20 0.34
POLB P06746 2/20 0.34
HPGD P15428 2/20 0.34
CASP1 P29466 2/20 0.34
HSD17B10 Q99714 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2788436 1.00 GSR (0.40) GSRHMGCRFFAR1SCN2AGAA
SCHEMBL12890012 1.00 GSR (0.40) GSRHMGCRFFAR1SCN2AGAA
SCHEMBL2788958 0.93 SCN2A (0.35) GSRHMGCRFFAR1SCN2AGAA
SCHEMBL14969560 0.90 GSR (0.39) GSRHMGCRFFAR1SCN2AGAA
SCHEMBL9912714 0.90 EGFR (0.32) GSRFFAR1EGFR
SCHEMBL2790487 0.85 HSPA5 (0.42) FFAR1GAAALDH1A1MEN1KMT2A
SCHEMBL12889972 0.85 EGFR (0.36) FFAR1GAAALDH1A1TSHREGFR
SCHEMBL2785061 0.85 EGFR (0.36) FFAR1GAAALDH1A1TSHREGFR
SCHEMBL2808828 0.85 HSPA5 (0.42) FFAR1GAAALDH1A1MEN1KMT2A
SCHEMBL9912715 0.85 GSR (0.38) GSRHMGCRFFAR1SCN2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-9388120-B2 Nitrogen and hindered phenol containing dual functional macromolecular antioxidants: synthesis, performances and applications POLNOX CORPORATION (US) 2016-07-12 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-20140316163-A1 NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS POLNOX CORPORATION (US) 2014-10-23 US disclosed
US-20130130955-A1 LUBRICANT OIL COMPOSITIONS POLNOX CORPORATION (US) 2013-05-23 US disclosed
US-20120142968-A1 Nitrogen and Hindered Phenol Containing Dual Functional Macromolecular Antioxidants: Synthesis, Performances and Applications POLNOX CORPORATION (US) 2012-06-07 US disclosed
US-20120004150-A1 Lubricant Oil Compositions POLNOX CORPORATION 2012-01-05 US disclosed
US-8080689-B2 Nitrogen and hindered phenol containing dual functional macromolecular antioxidants: synthesis, performances and applications POLNOX CORPORATION (US) 2011-12-20 US disclosed
US-20110040125-A1 NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS POLNOX CORPORATION (US) 2011-02-17 US disclosed
US-7799948-B2 stabilizers for inhibiting oxidation in organic materials, lubricants and petroleum based products, plastics and elastomers, cosmetics, foods and cooking oils POLNOX CORPORATION (US) 2010-09-21 US disclosed
US-7705075-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2010-04-27 US disclosed
US-7705075-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2010-04-27 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
WO-2007050991-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION (US) 2007-05-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140316163-A1 NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS CAT, LPO, DUOX1 GSR 54/4885HMGCR 2768/4885FFAR1 4072/4885
US-20120142968-A1 Nitrogen and Hindered Phenol Containing Dual Functional Macromolecular Antioxidants: Synthesis, Performances and Applications CAT, LPO, DUOX1 GSR 54/4885HMGCR 2768/4885FFAR1 4072/4885
US-20110040125-A1 NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS CAT, DUOX1, LPO GSR 54/4885HMGCR 2761/4885FFAR1 4106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.