Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 11/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 11/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27905011 | 0.83 | TAS1R3 (0.50) | TAS1R3TAS1R1LNPEPERAP1MAPK14 | |
| SCHEMBL27725302 | 0.83 | TAS1R3 (0.50) | TAS1R3TAS1R1LNPEPERAP1MAPK14 | |
| SCHEMBL16898289 | 0.75 | L3MBTL1 (0.55) | TAS1R3TAS1R1MAPK14CA12CA1 | |
| SCHEMBL16898288 | 0.75 | L3MBTL1 (0.55) | TAS1R3TAS1R1MAPK14CA12CA1 | |
| SCHEMBL8972761 | 0.72 | L3MBTL1 (0.52) | TAS1R3TAS1R1LNPEPMAPK14CA12 | |
| SCHEMBL9381373 | 0.72 | CA12 (0.41) | TAS1R3TAS1R1LNPEPERAP1MAPK14 | |
| SCHEMBL9381370 | 0.72 | CA12 (0.41) | TAS1R3TAS1R1LNPEPERAP1MAPK14 | |
| SCHEMBL28757793 | 0.71 | L3MBTL1 (0.51) | TAS1R3TAS1R1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL24142085 | 0.71 | L3MBTL1 (0.51) | TAS1R3TAS1R1LNPEPERAP1MAPK14 | |
| SCHEMBL28404546 | 0.71 | L3MBTL1 (0.51) | TAS1R3TAS1R1MAPK14CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103086912-A | Method for preparing pemetrexed and pemetrexed intermediate | HUBEI HALFSKY PHARMACY CO LTD | 2013-05-08 | — | — | CN | disclosed |