Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27905011 | 1.00 | TAS1R3 (0.50) | TAS1R3TAS1R1L3MBTL1LNPEPERAP1 | |
| SCHEMBL28757793 | 0.87 | L3MBTL1 (0.51) | TAS1R3TAS1R1L3MBTL1GAAKMT2A | |
| SCHEMBL27905010 | 0.83 | TAS1R3 (0.43) | TAS1R3TAS1R1L3MBTL1LNPEPERAP1 | |
| SCHEMBL27639464 | 0.80 | TAS1R3 (0.46) | TAS1R3TAS1R1L3MBTL1LNPEPCA12 | |
| SCHEMBL27639462 | 0.80 | TAS1R3 (0.46) | TAS1R3TAS1R1L3MBTL1LNPEPCA12 | |
| SCHEMBL7571102 | 0.80 | L3MBTL1 (0.53) | TAS1R3TAS1R1L3MBTL1KMT2A | |
| SCHEMBL8972761 | 0.79 | L3MBTL1 (0.52) | TAS1R3TAS1R1L3MBTL1LNPEPCA12 | |
| SCHEMBL28774100 | 0.79 | DHFR (0.58) | CA1CA2 | |
| SCHEMBL27546846 | 0.79 | DHFR (0.58) | CA1CA2 | |
| SCHEMBL24142085 | 0.78 | L3MBTL1 (0.51) | TAS1R3TAS1R1L3MBTL1LNPEPERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111087321-A | Purification method of pemetrexed disodium intermediate | 山东安弘制药有限公司 | 2020-05-01 | — | — | CN | disclosed |
| CN-103086912-A | Method for preparing pemetrexed and pemetrexed intermediate | HUBEI HALFSKY PHARMACY CO LTD | 2013-05-08 | — | — | CN | disclosed |
| CN-101333173-B | N-[4-(butanal-4-group)-benzoyl]-L-glutamic acid dimethyl ester compound and method for preparing pemetrexed by using the compounds | QILU PHARMACEUTICAL CO LTD | 2011-08-10 | — | — | CN | disclosed |
| CN-101333173-A | N-[4-(butanal-4-group)-benzoyl]-L-glutamic acid dimethyl ester compound and method for preparing pemetrexed by using the compounds | QILU PHARMACEUTICAL CO LTD (CN) | 2008-12-31 | — | — | CN | disclosed |