SCHEMBL2790583

SCHEMBL2790583

C=CC(=O)OOC(C)c1c(Br)cc(Br)cc1Br

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.32
▸ MAOA P21397 1/20 0.30
▸ MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28319483 0.74 TSHR (0.54) TSHRHSD17B10
SCHEMBL9187168 0.73 HCAR2 (0.39) TSHR
SCHEMBL2794002 0.73 TSHR (0.31) TSHR
SCHEMBL8579210 0.71 HSD17B10 (0.40) TSHRHSD17B10
SCHEMBL1508459 0.69 HSD17B10 (0.38) TSHRHSD17B10MAOAMAOB
SCHEMBL447804 0.68 GABRA1 (0.41) TSHRHSD17B10
SCHEMBL30486245 0.68 GABRA1 (0.41) TSHRHSD17B10
SCHEMBL8170444 0.67 — —
SCHEMBL316904 0.67 HSD17B10 (0.42) TSHRHSD17B10
Acrylic Acid Methyl Ester SCHEMBL9479959 0.67 TDP1 (0.50) TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2190652-B1 PROCESS FOR APPLYING A COATED OR UNCOATED FILM ON A LENS SUBSTRATE ESSILOR INT (FR) 2015-10-21 — — EP disclosed
US-8202392-B2 Process for applying a coated or uncoated film on a lens substrate ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2012-06-19 — — US disclosed
US-20100163165-A1 Process for Applying a Coated or Uncoated Film on a Lens Substrate ESSILOR INTERNATIONAL (COMPAGINE GENERALE D'OPTIQU (FR) 2010-07-01 — — US disclosed
EP-2190652-A1 PROCESS FOR APPLYING A COATED OR UNCOATED FILM ON A LENS SUBSTRATE Essilor International (Compagnie Générale D'Optique) (FR) 2010-06-02 — — EP disclosed
WO-2009019276-A1 PROCESS FOR APPLYING A COATED OR UNCOATED FILM ON A LENS SUBSTRATE ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2009-02-12 — — WO disclosed
Send feedback