SCHEMBL447804

SCHEMBL447804

C=CC(=O)Oc1c(Br)cc(Br)cc1C(C)C

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
HSD17B10 Q99714 1/20 0.37
THRB P10828 6/20 0.37
THRA P10827 5/20 0.37
TSHR P16473 1/20 0.35
NLRP3 Q96P20 1/20 0.32
LMNA P02545 1/20 0.31
ALOX12 P18054 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30486245 1.00 GABRA1 (0.41) GABRA1GABRB1HSD17B10THRBTHRA
SCHEMBL448738 0.86 THRB (0.35) GABRA1GABRB1HSD17B10THRBTHRA
SCHEMBL30004700 0.86 THRB (0.35) GABRA1GABRB1HSD17B10THRBTHRA
SCHEMBL316904 0.84 HSD17B10 (0.42) GABRA1GABRB1HSD17B10THRBTHRA
SCHEMBL7066921 0.81 THRB (0.43) GABRA1GABRB1HSD17B10THRBTHRA
SCHEMBL3742121 0.79 TSHR (0.46) GABRA1GABRB1HSD17B10THRBTHRA
SCHEMBL7618929 0.79 GABRA1 (0.41) GABRA1GABRB1HSD17B10THRBTHRA
SCHEMBL5899725 0.75 HSD17B10 (0.36) HSD17B10THRB
SCHEMBL10587663 0.75 HSD17B10 (0.36) HSD17B10THRB
SCHEMBL7067451 0.74 GPR35 (0.42) GABRA1GABRB1HSD17B10THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8241755-B2 Polymerizable composition comprising low molecular weight organic component 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-08-14 US claimed
US-20110318538-A1 POLYMERIZABLE COMPOSITION COMPRISING LOW MOLECULAR WEIGHT ORGANIC COMPONENT 3M INNOVATIVE PROPERTIES COMPANY 2011-12-29 US claimed
US-8034421-B2 Polymerizable composition comprising low molecular weight organic component 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-10-11 US claimed
US-8025934-B2 Polymerizable composition comprising low molecular weight organic component 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-09-27 US claimed
US-20100331442-A1 POLYMERIZABLE COMPOSITION COMPRISING LOW MOLECULAR WEIGHT ORGANIC COMPONENT 3M INNOVATIVE PROPERTIES COMPANY 2010-12-30 US claimed
US-20080253148-A1 Polymerizable Composition Comprising Low Molecular Weight Organic Component 3M INNOVATIVE PROPERTIES COMPANY 2008-10-16 US claimed
EP-1861735-A2 POLYMERIZABLE COMPOSITION COMPRISING LOW MOLECULAR WEIGHT ORGANIC COMPONENT 3M Innovative Properties Company (US) 2007-12-05 EP claimed
WO-2006099357-A2 POLYMERIZABLE COMPOSITION COMPRISING LOW MOLECULAR WEIGHT ORGANIC COMPONENT 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-09-21 WO claimed
US-20060204676-A1 Polymerizable composition comprising low molecular weight organic component 3M INNOVATIVE PROPERTIES COMPANY 2006-09-14 US claimed
US-12552087-B2 Method of thermoforming film with structured surface and articles SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-02-17 US disclosed
US-12286396-B2 Dicarboxylic acid compounds, inorganic particles treated with the dicarboxylic acid compounds, and compositions thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-04-29 US disclosed
CN-114585604-B Dicarboxylic acid compounds, inorganic particles and compositions thereof treated with dicarboxylic acid compounds 3M创新有限公司 2024-02-02 CN disclosed
EP-3973020-B1 COMPOSITION COMPRISING STYRENE ISOPRENE BLOCK COPOLYMER AND ETHYLENICALLY UNSATURATED MONOMER 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-01-17 EP disclosed
US-20230390991-A1 METHOD OF THERMOFORMING FILM WITH STRUCTURED SURFACE AND ARTICLES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-12-07 US disclosed
US-20060210726-A1 Brightness enhancing film; use with displays to improve energy efficiency due to higher gain (brightness); optical film with microstructured surface such as repeating pattern of linear prisms 3M INNOVATIVE PROPERTIES COMPANY 2006-09-21 US disclosed
US-20060204676-A1 Polymerizable composition comprising low molecular weight organic component 3M INNOVATIVE PROPERTIES COMPANY 2006-09-14 US disclosed
WO-2006088930-A2 BRIGHTNESS ENHANCEMENT FILM COMPRISING POLYMERIZED ORGANIC PHASE HAVING LOW GLASS TRANSITION TEMPERATURE 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-08-24 WO disclosed
US-20060187366-A1 MICROSTRUCTURED ARTICLE COMPRISING A POLYMERIZED COMPOSITION HAVING LOW GLASS TRANSITION TEMPERATURE 3M INNOVATIVE PROPERTIES COMPANY 2006-08-24 US disclosed
WO-2006028543-A2 OPTICAL FILM, ASSEMBLY AND DISPLAY DEVICE 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-03-16 WO disclosed
US-20050200278-A1 Polymerizable compositions comprising nanoparticles 3M INNOVATIVE PROPERTIES COMPANY 2005-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12286396-B2 Dicarboxylic acid compounds, inorganic particles treated with the dicarboxylic acid compounds, and compositions thereof F12, RCC1, C9 GABRA1 734/4885GABRB1 2319/4885HSD17B10 1397/4885
US-12552087-B2 Method of thermoforming film with structured surface and articles TPM3, TLL1, TPM4 GABRA1 3535/4885GABRB1 3878/4885HSD17B10 2721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.