Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | FNTA | P49354 | 4/20 | 0.39 |
| ▸ | FNTB | P49356 | 4/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28038609 | 0.81 | TACR1 (0.43) | TACR1HRH3TAAR1CHRM3SIGMAR1 | |
| SCHEMBL28046374 | 0.77 | HPGD (0.48) | S1PR1SIGMAR1 | |
| SCHEMBL28929394 | 0.77 | TRPV6 (0.45) | CYP3A4CYP2C9KDM1ASIGMAR1 | |
| SCHEMBL27889766 | 0.73 | KDM4B (0.33) | — | |
| SCHEMBL5052610 | 0.72 | HPGD (0.60) | FNTAFNTBTAAR1CHRM3 | |
| SCHEMBL27474231 | 0.71 | HRH3 (0.60) | HRH3CHRM3SIGMAR1 | |
| SCHEMBL27889765 | 0.71 | DRD4 (0.40) | — | |
| Hydrochloric Acid SCHEMBL27408448 | 0.70 | HRH3 (0.59) | HRH3CHRM3SIGMAR1 | |
| SCHEMBL27653211 | 0.69 | TBXAS1 (0.39) | CYP3A4CYP2D6 | |
| SCHEMBL27889785 | 0.69 | DRD4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109662961-A | For improving the method and composition of cognitive function | 约翰斯霍普金斯大学 | 2019-04-23 | — | — | CN | disclosed |
| CN-109662964-A | For improving the method and composition of cognitive function | 约翰斯.霍普金斯大学 | 2019-04-23 | — | — | CN | disclosed |
| CN-105142623-A | Methods and compositions for improving cognitive function | AGENEBIO INC | 2015-12-09 | — | — | CN | disclosed |
| CN-103476255-A | Methods and compositions for improving cognitive function | UNIV JOHNS HOPKINS | 2013-12-25 | — | — | CN | disclosed |
| CN-102905532-A | Methods and compositions for improving cognitive function | UNIV JOHNS HOPKINS | 2013-01-30 | — | — | CN | disclosed |