Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.64 |
| ▸ | ACR | P10323 | 2/20 | 0.57 |
| ▸ | ALPL | P05186 | 10/20 | 0.54 |
| ▸ | CA12 | O43570 | 4/20 | 0.54 |
| ▸ | RPA1 | P27694 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | TACR3 | P29371 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2566128 | 0.89 | ALPL (0.69) | SNCAACRALPLCA12RPA1 | |
| SCHEMBL4090739 | 0.83 | ALPL (0.70) | SNCAACRALPLCA12CA9 | |
| SCHEMBL14290127 | 0.79 | ALPL (0.51) | SNCAACRALPLCA12CA9 | |
| SCHEMBL21856003 | 0.78 | SNCA (0.53) | SNCAACRALPLCA12TACR3 | |
| SCHEMBL27887288 | 0.78 | TP53 (0.79) | ACRALPLCA12RPA1CA9 | |
| Hydrochloric Acid SCHEMBL28800536 | 0.76 | TP53 (0.77) | ACRALPLCA12RPA1CA9 | |
| SCHEMBL1924736 | 0.76 | TP53 (0.55) | SNCAACRALPLCA12RPA1 | |
| SCHEMBL2826440 | 0.75 | SNCA (0.48) | SNCAACRTACR3TP53MAPT | |
| SCHEMBL29897026 | 0.75 | CASP1 (0.58) | SNCAACRTACR3TP53MAPT | |
| SCHEMBL28015306 | 0.75 | BACE1 (0.49) | SNCAACRALPLCA12RPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102906093-A | Novel nk-3 receptor selective antagonist compounds, pharmaceutical composition and methods for use in nk-3 receptors mediated disorders | EUROSCREEN SA | 2013-01-30 | — | — | CN | claimed |