SCHEMBL28015306

SCHEMBL28015306

CC(=O)Oc1cc(-c2ccc(C(F)(F)F)cc2)n[nH]1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.49
SNCA P37840 2/20 0.48
ADORA3 P0DMS8 1/20 0.44
ACR P10323 2/20 0.44
TACR3 P29371 1/20 0.43
KDM4E B2RXH2 2/20 0.43
USP2 O75604 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
CYP2C19 P33261 1/20 0.43
HSD17B10 Q99714 1/20 0.43
NR1H4 Q96RI1 1/20 0.41
MAPT P10636 3/20 0.40
POLB P06746 2/20 0.40
TP53 P04637 1/20 0.40
KIF11 P52732 1/20 0.40
THRB P10828 1/20 0.40
CASP1 P29466 1/20 0.39
ALPL P05186 4/20 0.39
CA9 Q16790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27909175 0.84 ALPL (0.55) TACR3USP2MAPTALPLCA9
SCHEMBL27906348 0.81 GAA (0.55) BACE1ADORA3ACRMAPTPOLB
SCHEMBL27906337 0.75 SNCA (0.64) SNCAACRTACR3KDM4EMAPT
SCHEMBL2566128 0.74 ALPL (0.69) SNCAACRTACR3KDM4ETP53
SCHEMBL3051778 0.72 NPC1 (0.61) SNCAACRKDM4ECYP2C19NR1H4
SCHEMBL21856003 0.72 SNCA (0.53) SNCAACRTACR3KDM4EMAPT
SCHEMBL4090739 0.72 ALPL (0.70) SNCAACRMAPTPOLBTP53
SCHEMBL1925415 0.72 SNCA (0.48) SNCAADORA3ACRTACR3KDM4E
SCHEMBL27842915 0.71 BACE1 (0.48) BACE1ADORA3KDM4EUSP2ALDH1A1
SCHEMBL7841174 0.71 RAF1 (0.49) SNCAKDM4EMAPTPOLBTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102317263-B Halogen substituted compounds as pesticides BAYER IP GMBH 2015-04-22 CN disclosed