Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.55 |
| ▸ | FBP1 | P09467 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27906513 | 0.89 | EGFR (0.54) | EGFRFBP1MAPTALDH1A1AURKB | |
| SCHEMBL27442491 | 0.89 | EGFR (0.68) | EGFRFBP1MAPTAURKBKDM4E | |
| SCHEMBL28109591 | 0.83 | EGFR (0.66) | EGFRMAPTMEN1ALDH1A1TNF | |
| SCHEMBL27441184 | 0.79 | EGFR (0.60) | EGFRFBP1ABCG2AURKBKDM4E | |
| Hydrochloric Acid SCHEMBL28040048 | 0.77 | AURKB (0.58) | EGFRFBP1MAPTMAPK1ABCG2 | |
| SCHEMBL27544914 | 0.76 | EGFR (0.62) | EGFRABCG2AURKBKDM4E | |
| SCHEMBL30820443 | 0.73 | EGFR (0.63) | EGFRFBP1MAPTMEN1ALDH1A1 | |
| SCHEMBL20637508 | 0.73 | EGFR (0.58) | EGFRFBP1MAPTMEN1ALDH1A1 | |
| SCHEMBL29168705 | 0.73 | EGFR (0.63) | EGFRFBP1MAPTMEN1ALDH1A1 | |
| SCHEMBL7216285 | 0.71 | EGFR (1.00) | EGFRFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102875570-B | Quinazoline derivant and its production and use | ZHEJIANG UNIVERSITY (CN) | 2015-11-04 | — | — | CN | disclosed |
| CN-102875570-A | Quinazoline derivative, and preparation method and application thereof | UNIV ZHEJIANG | 2013-01-16 | — | — | CN | disclosed |