Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2223747 | 0.82 | NOTUM (0.42) | NOTUM | |
| SCHEMBL201964 | 0.81 | MEN1 (0.30) | — | |
| SCHEMBL17200853 | 0.73 | MEN1 (0.39) | HSD17B1HSD17B2 | |
| SCHEMBL17200836 | 0.73 | MEN1 (0.39) | HSD17B1HSD17B2 | |
| SCHEMBL27907113 | 0.72 | KDM4E (0.30) | — | |
| SCHEMBL3136165 | 0.70 | ALDH1A1 (0.51) | HSD17B1HSD17B2 | |
| SCHEMBL1510123 | 0.69 | ALDH1A1 (0.37) | HSD17B1HSD17B2 | |
| SCHEMBL1532000 | 0.69 | ACHE (0.44) | — | |
| SCHEMBL2095103 | 0.69 | HSD17B1 (0.46) | HSD17B1HSD17B2 | |
| SCHEMBL610112 | 0.69 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933214-A | 4,4-disubstituted piperidine derivatives useful as inhibitors of dipeptidyl peptidase-1 (dpp-1) | JANSSEN PHARMACEUTICA NV | 2013-02-13 | — | — | CN | claimed |
| CN-102933214-A | 4,4-disubstituted piperidine derivatives useful as inhibitors of dipeptidyl peptidase-1 (dpp-1) | JANSSEN PHARMACEUTICA NV | 2013-02-13 | — | — | CN | disclosed |