SCHEMBL27907484

SCHEMBL27907484

NC(=O)OCCC1=NN(CC2CCC2)C(=O)C1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.36
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27907493 0.97 PDE4B (0.34) PDE4BLMNA
SCHEMBL27925593 0.96 LMNA (0.33) PDE4BLMNA
SCHEMBL27907522 0.95 LMNA (0.31) PDE4BLMNA
SCHEMBL27925621 0.85 L3MBTL1 (0.33)
SCHEMBL27925573 0.82
SCHEMBL361567 0.76 POLB (0.35) PDE4B
SCHEMBL27925589 0.76
SCHEMBL27925615 0.75 LMNA (0.49) LMNA
SCHEMBL27907491 0.74
SCHEMBL27925651 0.74 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103097357-A Pyrazole compound DAINIPPON SUMITOMO PHARMA CO 2013-05-08 CN disclosed