Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.62 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16706895 | 0.86 | ABCG2 (0.47) | ABCG2PDK2AGTR1AGTR2PPARA | |
| SCHEMBL344042 | 0.84 | RAB9A (0.53) | PPARANPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL20767128 | 0.81 | ABCG2 (0.43) | ABCG2PDK2AGTR1AGTR2PPARA | |
| SCHEMBL13846109 | 0.79 | PDK2 (0.48) | ABCG2PDK2NPC1RAB9ANFKB1 | |
| SCHEMBL13892312 | 0.79 | ABCG2 (0.58) | ABCG2RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2316723 | 0.79 | NPC1 (0.52) | PPARANPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL16706894 | 0.78 | AGTR1 (0.43) | ABCG2PDK2AGTR1AGTR2NPC1 | |
| SCHEMBL2647877 | 0.78 | PDK2 (0.50) | PDK2SMN1; SMN2GRM5 | |
| SCHEMBL8212790 | 0.76 | ACLY (0.53) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL13846219 | 0.75 | NPSR1 (0.58) | PDK2NPC1RAB9ASMN1; SMN2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103179976-A | Glucagon superfamily peptides exhibiting g protein-coupled receptor activity | MARCADIA BIOTECH INC | 2013-06-26 | — | — | CN | disclosed |