Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 9/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878983 | 0.81 | PBRM1 (0.57) | PBRM1PIM1PIM3JAK2TP53 | |
| SCHEMBL29605233 | 0.81 | PIM3 (0.65) | PBRM1PIM1PIM3JAK2TP53 | |
| SCHEMBL145574 | 0.81 | PIM3 (0.65) | PBRM1PIM1PIM3JAK2TP53 | |
| SCHEMBL4654498 | 0.81 | PBRM1 (0.60) | PBRM1PIM1PIM3JAK2TP53 | |
| Hydrochloric Acid SCHEMBL28165797 | 0.80 | PIM3 (0.63) | PBRM1PIM1PIM3JAK2TP53 | |
| Hydrochloric Acid SCHEMBL28848226 | 0.80 | PIM3 (0.63) | PBRM1PIM1PIM3JAK2TP53 | |
| SCHEMBL29844370 | 0.80 | PBRM1 (0.78) | PBRM1PIM1PIM3JAK2TP53 | |
| SCHEMBL143999 | 0.80 | PBRM1 (0.78) | PBRM1PIM1PIM3JAK2TP53 | |
| SCHEMBL6887279 | 0.80 | PBRM1 (0.58) | PBRM1PIM1PIM3JAK2TP53 | |
| SCHEMBL30455267 | 0.80 | PBRM1 (0.78) | PBRM1PIM1PIM3JAK2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112375029-B | Carbazole alkaloid derivative and preparation method and application thereof | 湖北省生物农药工程研究中心 | 2022-03-18 | — | — | CN | claimed |
| CN-112375029-A | Carbazole alkaloid derivative and preparation method and application thereof | 湖北省生物农药工程研究中心 | 2021-02-19 | — | — | CN | claimed |
| CN-102936332-B | Narrow band gap conjugated polymer material with side chain provided with dendritic carbazole groups, and preparation method and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2015-01-14 | — | — | CN | claimed |
| CN-102936332-A | Narrow band gap conjugated polymer material with side chain provided with dendritic carbazole groups, and preparation method and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2013-02-20 | — | — | CN | claimed |
| CN-112375029-B | Carbazole alkaloid derivative and preparation method and application thereof | 湖北省生物农药工程研究中心 | 2022-03-18 | — | — | CN | disclosed |
| CN-112375029-A | Carbazole alkaloid derivative and preparation method and application thereof | 湖北省生物农药工程研究中心 | 2021-02-19 | — | — | CN | disclosed |
| CN-102936332-A | Narrow band gap conjugated polymer material with side chain provided with dendritic carbazole groups, and preparation method and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2013-02-20 | — | — | CN | disclosed |