Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 2/20 | 0.65 |
| ▸ | PIM1 | P11309 | 1/20 | 0.65 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 4/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 3/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | MAP2 | P11137 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29605233 | 1.00 | PIM3 (0.65) | PIM3PIM1PBRM1HSD17B10ALOX15 | |
| Hydrochloric Acid SCHEMBL28165797 | 0.98 | PIM3 (0.63) | PIM3PIM1PBRM1HSD17B10ALOX15 | |
| Hydrochloric Acid SCHEMBL28848226 | 0.98 | PIM3 (0.63) | PIM3PIM1PBRM1HSD17B10ALOX15 | |
| SCHEMBL4960238 | 0.88 | PBRM1 (0.74) | PIM3PIM1PBRM1HSD17B10ALOX15 | |
| SCHEMBL4654498 | 0.85 | PBRM1 (0.60) | PIM3PIM1PBRM1HSD17B10ALDH1A1 | |
| SCHEMBL6887279 | 0.84 | PBRM1 (0.58) | PIM3PIM1PBRM1HSD17B10ALDH1A1 | |
| SCHEMBL143999 | 0.84 | PBRM1 (0.78) | PIM3PIM1PBRM1KIF11JAK2 | |
| SCHEMBL30455267 | 0.84 | PBRM1 (0.78) | PIM3PIM1PBRM1KIF11JAK2 | |
| SCHEMBL29844370 | 0.84 | PBRM1 (0.78) | PIM3PIM1PBRM1KIF11JAK2 | |
| SCHEMBL27864716 | 0.83 | PIM3 (0.61) | PIM3PIM1PBRM1HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 430 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184570-A | Carbazole amide derivative, preparation method and application thereof | 中国海洋大学 | 2024-06-14 | — | — | CN | claimed |
| CN-116041248-B | Carbazole derivative with anticancer activity and preparation method and application thereof | 成都摩诃大龙医药科技有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-116041248-A | Carbazole derivative with anticancer activity and preparation method and application thereof | 成都摩诃大龙医药科技有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-109206360-B | Carbazole amide derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2022-05-17 | — | — | CN | claimed |
| CN-109206360-A | Carbazole amide derivatives or its salt and its preparation method and application | 复旦大学 | 2019-01-15 | — | — | CN | claimed |
| CN-105473573-B | Carbazole carboxamide compounds useful as kinase inhibitor | 百时美施贵宝公司 | 2018-03-16 | — | — | CN | claimed |
| EP-3209651-A1 | CARBAZOLE DERIVATIVES | Bristol-Myers Squibb Company (US) | 2017-08-30 | — | — | EP | claimed |
| CN-107108555-A | Three ring atropisomer compounds | 百时美施贵宝公司 | 2017-08-29 | — | — | CN | claimed |
| CN-107074804-A | Carbazole derivates | 百时美施贵宝公司 | 2017-08-18 | — | — | CN | claimed |
| CN-102370967-A | Novel application of IL-1Ra (interleukin-1 receptor antagonist) and tumor treatment medicinal composition kit thereof | UNIV SHANGHAI JIAOTONG | 2012-03-14 | — | — | CN | claimed |
| WO-2008141189-A1 | GHRELIN MODULATING COMPOUNDS AND COMBINATIONS THEREOF | ELIXIR PHARMACEUTICALS, INC. (US) | 2008-11-20 | — | — | WO | claimed |
| EP-1044197-B1 | PIPERIDINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKYNE CARBOXAMIDES AS CYTOSTATIC AGENTS AND IMMUNOSUPPRESSANTS | ASTELLAS PHARMA GMBH (DE) | 2006-04-19 | — | — | EP | claimed |
| EP-1599202-A1 | TETRACYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Pharmacia Italia S.p.A. (IT) | 2005-11-30 | — | — | EP | claimed |
| EP-1572239-A1 | METHOD OF USING A COX-2 INHIBITOR AND A TOPOISOMERASE II INHIBITOR AS A COMBINATION THERAPY IN THE TREATMENT OF NEOPLASIA | Pharmacia Corporation (US) | 2005-09-14 | — | — | EP | claimed |
| WO-2004071507-A1 | TETRACYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PHARMACIA ITALIA S.P.A. (IT) | 2004-08-26 | — | — | WO | claimed |
| WO-2004058302-A1 | METHOD OF USING A COX-2 INHIBITOR AND A TOPOISOMERASE II INHIBITOR AS A COMBINATION THERAPY IN THE TREATMENT OF NEOPLASIA | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | claimed |
| US-6593344-B1 | These substances have especially high cytostatic activities and pronounced immunosuppressive properties which make them suitable for therapeutic treatment in broad tumor spectrum and autoimmune diseases | KLINGE PHARMA GMBH (DE) | 2003-07-15 | — | — | US | claimed |
| EP-1044197-A2 | NEW PIPERIDINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES | Klinge Pharma GmbH (DE) | 2000-10-18 | — | — | EP | claimed |
| WO-1999031060-A2 | PIPERIDINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES AS CYTOSTATICS AND IMMUNESUPPRESSANTS | KLINGE PHARMA GMBH (DE) | 1999-06-24 | — | — | WO | claimed |
| US-12577261-B2 | Carbene compounds and organic electroluminescent devices | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2026-03-17 | — | — | US | disclosed |
| CN-120424000-A | Polysubstituted carbazole amide derivative, preparation method and application thereof | 湖北省生物农药工程研究中心 | 2025-08-05 | — | — | CN | disclosed |
| CN-119798140-A | Continuous synthesis method of perdeuterated carbazole | 上海亚兴生物医药科技有限公司 | 2025-04-11 | — | — | CN | disclosed |
| US-12180230-B2 | Carbene compounds and organic electroluminescent devices | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2024-12-31 | — | — | US | disclosed |
| CN-118993985-A | Compound with anti-tumor activity, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-11-22 | — | — | CN | disclosed |
| CN-118546088-B | Method and system for co-producing N-ethylcarbazole and N-ethylaniline | 陕西氢易能源科技有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-118546088-A | Method and system for co-producing N-ethylcarbazole and N-ethylaniline | 陕西氢易能源科技有限公司 | 2024-08-27 | — | — | CN | disclosed |
| EP-3878855-B1 | CARBENE COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | UNIV SOUTHERN CALIFORNIA (US) | 2024-06-19 | — | — | EP | disclosed |
| CN-118184570-A | Carbazole amide derivative, preparation method and application thereof | 中国海洋大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-118184570-A | Carbazole amide derivative, preparation method and application thereof | 中国海洋大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-118184570-A | Carbazole amide derivative, preparation method and application thereof | 中国海洋大学 | 2024-06-14 | — | — | CN | disclosed |
| US-11873494-B2 | Genetic and pharmacological transcriptional upregulation of the repressed FXN gene as a therapeutic strategy for Friedreich ataxia | UNIVERSITY OF MASSACHUSETTS (US) | 2024-01-16 | — | — | US | disclosed |
| US-20230250111-A1 | CARBENE COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2023-08-10 | — | — | US | disclosed |
| CN-116041248-B | Carbazole derivative with anticancer activity and preparation method and application thereof | 成都摩诃大龙医药科技有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-111320564-B | Room temperature phosphorescent material with excitation wavelength dependence and preparation method and application thereof | 湖州师范学院 | 2023-05-23 | — | — | CN | disclosed |
| CN-116041248-A | Carbazole derivative with anticancer activity and preparation method and application thereof | 成都摩诃大龙医药科技有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-115917374-A | Infrared absorbing composition, film, optical filter, solid-state imaging element, image display device, and infrared sensor | 富士胶片株式会社 | 2023-04-04 | — | — | CN | disclosed |
| CN-115768833-A | Resin composition, film, optical filter, solid-state imaging element, image display device, resin, and compound | 富士胶片株式会社 | 2023-03-07 | — | — | CN | disclosed |
| CN-115427517-A | Coloring composition, film, optical filter, solid-state imaging element, and image display device | 富士胶片株式会社 | 2022-12-02 | — | — | CN | disclosed |
| CN-109206360-B | Carbazole amide derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-109206360-B | Carbazole amide derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-109206360-B | Carbazole amide derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2022-05-17 | — | — | CN | disclosed |
| US-20220042023-A1 | Genetic and Pharmacological Transcriptional Upregulation of the Repressed FXN Gene as a Therapeutic Strategy for Friedreich Ataxia | UNIVERSITY OF MASSACHUSETTS | 2022-02-10 | — | — | US | disclosed |
| US-11124795-B2 | Genetic and pharmacological transcriptional upregulation of the repressed FXN gene as a therapeutic strategy for Friedreich ataxia | UNIVERSITY OF MASSACHUSETTS (US) | 2021-09-21 | — | — | US | disclosed |
| EP-3878855-A1 | CARBENE COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | University of Southern California (US) | 2021-09-15 | — | — | EP | disclosed |
| US-11053197-B2 | Carbazole derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-07-06 | — | — | US | disclosed |
| CN-112876406-A | Deuterated carbazole compound, preparation method thereof, photoelectric material and medicine | 安徽秀朗新材料科技有限公司 | 2021-06-01 | — | — | CN | disclosed |
| EP-3489243-B1 | CARBENE COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | UNIV SOUTHERN CALIFORNIA (US) | 2021-04-21 | — | — | EP | disclosed |
| CN-111039925-B | Pyridine-based organic room temperature phosphorescent compound and preparation and application thereof | 浙江工业大学 | 2021-01-01 | — | — | CN | disclosed |
| CN-107108555-B | Tricyclic atropisomer compounds | 百时美施贵宝公司 | 2020-12-01 | — | — | CN | disclosed |
| EP-3558977-B1 | PROCESS FOR PREPARING TETRAHYDROCARBAZOLE CARBOXAMIDE COMPOUND | BRISTOL MYERS SQUIBB CO (US) | 2020-10-28 | — | — | EP | disclosed |
| US-20200255377-A1 | CARBAZOLE DERIVATIVES | Organization Name: BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-08-13 | — | — | US | disclosed |
| EP-3681493-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER CACHEXIA | The Ohio State Innovation Foundation (US) | 2020-07-22 | — | — | EP | disclosed |
| CN-111320564-A | Room-temperature phosphorescent material with dependent excitation wavelength as well as preparation method and application thereof | 湖州师范学院 | 2020-06-23 | — | — | CN | disclosed |
| US-10676434-B2 | Carbazole derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-06-09 | — | — | US | disclosed |
| EP-3209651-B9 | CARBAZOLE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2020-05-20 | — | — | EP | disclosed |
| CN-111039925-A | Pyridine-based organic room temperature phosphorescent compound and preparation and application thereof | 浙江工业大学 | 2020-04-21 | — | — | CN | disclosed |
| EP-3209652-B1 | TRICYCLIC ATROPISOMER COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-04-15 | — | — | EP | disclosed |
| CN-107074804-B | Carbazole derivatives | 百时美施贵宝公司 | 2020-02-18 | — | — | CN | disclosed |
| WO-2020015615-A1 | ALKYNYL (HETERO) AROMATIC RING COMPOUNDS USED FOR INHIBITING PROTEIN KINASE ACTIVITY | 深圳市塔吉瑞生物医药有限公司 | 2020-01-23 | — | — | WO | disclosed |
| WO-2020007234-A1 | ALKYNYL(HETERO)AROMATIC COMPOUND FOR INHIBITING PROTEIN KINASE ACTIVITY | 深圳市塔吉瑞生物医药有限公司 | 2020-01-09 | — | — | WO | disclosed |
| EP-3209651-B1 | CARBAZOLE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2019-10-23 | — | — | EP | disclosed |
| US-10435415-B2 | Substituted tetrahydrocarbazole and carbazole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-10-08 | — | — | US | disclosed |
| US-10435415-B2 | Substituted tetrahydrocarbazole and carbazole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-10-08 | — | — | US | disclosed |
| CN-110312713-A | Process for preparing tetrahydrocarbazole carboxamide compounds | 百时美施贵宝公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-110194772-A | For inhibiting (miscellaneous) the fragrant cyclics of the alkynyl of protein kinase activity | 深圳市塔吉瑞生物医药有限公司 | 2019-09-03 | — | — | CN | disclosed |
| EP-3042903-B1 | Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof | IMPETIS BIOSCIENCES LTD (IN) | 2019-08-14 | — | — | EP | disclosed |
| US-20190225583-A1 | CARBAZOLE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2019-07-25 | — | — | US | disclosed |
| CN-109890846-A | anti-CD 27 antibodies | 默沙东公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-109851620-A | For inhibiting the condensed-bicyclic class compound of tyrosine kinase activity | 深圳市塔吉瑞生物医药有限公司 | 2019-06-07 | — | — | CN | disclosed |
| CN-109836441-A | Carbene compound and Organnic electroluminescent device | 南加州大学 | 2019-06-04 | — | — | CN | disclosed |
| US-20190161504-A1 | CARBENE COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2019-05-30 | — | — | US | disclosed |
| EP-3489243-A1 | CARBENE COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | University of Southern California (US) | 2019-05-29 | — | — | EP | disclosed |
| CN-109803686-A | Composition comprising source metal, dithiocar-bamate and cyclodextrin | 德国癌症研究公共权益基金会 | 2019-05-24 | — | — | CN | disclosed |
| CN-108368119-B | Fused Bicyclic Compounds for Inhibiting Tyrosine Kinase Activity | 深圳市塔吉瑞生物医药有限公司 | 2019-04-23 | — | — | CN | disclosed |
| US-10266491-B2 | Carbazole derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-23 | — | — | US | disclosed |
| WO-2019055687-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER CACHEXIA | OHIO STATE INNOVATION FOUNDATION (US) | 2019-03-21 | — | — | WO | disclosed |
| CN-106543070-B | Carbazole-amides room temperature phosphorimetry molecule and its preparation method and application that N replaces | 武汉大学 | 2019-03-01 | — | — | CN | disclosed |
| CN-106543070-B | Carbazole-amides room temperature phosphorimetry molecule and its preparation method and application that N replaces | 武汉大学 | 2019-03-01 | — | — | CN | disclosed |
| CN-105307656-B | Quinoline inhibitors of macrophage stimulating 1 receptor MST1R | 利德发现中心有限责任公司 | 2019-02-19 | — | — | CN | disclosed |
| US-20190023719-A1 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2019-01-24 | — | — | US | disclosed |
| CN-109206360-A | Carbazole amide derivatives or its salt and its preparation method and application | 复旦大学 | 2019-01-15 | — | — | CN | disclosed |
| CN-109206360-A | Carbazole amide derivatives or its salt and its preparation method and application | 复旦大学 | 2019-01-15 | — | — | CN | disclosed |
| CN-109206360-A | Carbazole amide derivatives or its salt and its preparation method and application | 复旦大学 | 2019-01-15 | — | — | CN | disclosed |
| WO-2019007284-A1 | CARBAZOLAMIDE DERIVATIVE OR SALT THEREOF AND PREPARATION METHOD THEREFOR AND USE THEREOF | 复旦大学 | 2019-01-10 | — | — | WO | disclosed |
| US-10106559-B2 | Substituted tetrahydrocarbazole and carbazole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-10-23 | — | — | US | disclosed |
| US-10106559-B2 | Substituted tetrahydrocarbazole and carbazole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-10-23 | — | — | US | disclosed |
| CN-108473476-A | Alkynyl heterocyclic compounds for inhibiting protein kinase activity | 深圳市塔吉瑞生物医药有限公司 | 2018-08-31 | — | — | CN | disclosed |
| EP-3362059-A1 | NEW COMBINATION THERAPIES FOR TREATING NEUROLOGICAL DAMAGE | Universitat Autònoma De Barcelona (ES) | 2018-08-22 | — | — | EP | disclosed |
| CN-108368119-A | Fused bicyclic compounds for inhibiting tyrosine kinase activity | 深圳市塔吉瑞生物医药有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-105189488-B | Carbazole compound as bromodomain inhibitor | 百时美施贵宝公司 | 2018-07-24 | — | — | CN | disclosed |
| US-10023534-B2 | Carbazole and tetrahydrocarbazole compounds useful as inhibitors of BTK | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-07-17 | — | — | US | disclosed |
| CN-108289922-A | Therapeutic methods and compositions for treating non-small cell lung cancer | 友杏生技医药股份有限公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-108135863-A | For treating the EGR1 targeted moleculars of inflammatory and the excess proliferative patient's condition | 特拉维夫医疗中心医学研究基础设施和保健服务基金会 | 2018-06-08 | — | — | CN | disclosed |
| CN-102958930-B | [1,8] naphthyridine compounds as the 2,4- diaryl substitution for the kinase inhibitor to anticancer | 默克专利有限公司 | 2018-04-27 | — | — | CN | disclosed |
| CN-105050598-B | Novel compounds as ERK inhibitors | 默沙东公司 | 2018-04-27 | — | — | CN | disclosed |
| US-20180079758-A1 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-22 | — | — | US | disclosed |
| CN-105473573-B | Carbazole carboxamide compounds useful as kinase inhibitor | 百时美施贵宝公司 | 2018-03-16 | — | — | CN | disclosed |
| CN-105473573-B | Carbazole carboxamide compounds useful as kinase inhibitor | 百时美施贵宝公司 | 2018-03-16 | — | — | CN | disclosed |
| US-9850258-B2 | Substituted tetrahydrocarbazole and carbazole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-26 | — | — | US | disclosed |
| US-9850258-B2 | Substituted tetrahydrocarbazole and carbazole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-26 | — | — | US | disclosed |
| US-20170362176-A1 | CARBAZOLE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-21 | — | — | US | disclosed |
| US-20170355673-A1 | TRICYCLIC ATROPISOMER COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2017-12-14 | — | — | US | disclosed |
| CN-105712991-B | 7 7-azaindole derivatives | 默克专利股份公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-105732617-B | 7 7-azaindole derivatives | 默克专利股份公司 | 2017-12-01 | — | — | CN | disclosed |
| EP-2892880-B1 | INDOLE CARBOXAMIDE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2017-11-22 | — | — | EP | disclosed |
| CN-105358546-B | The tetrahydro carbazole being substituted and carbazole carboxamide compounds useful as kinase inhibitor | 百时美施贵宝公司 | 2017-10-31 | — | — | CN | disclosed |
| CN-105358546-B | The tetrahydro carbazole being substituted and carbazole carboxamide compounds useful as kinase inhibitor | 百时美施贵宝公司 | 2017-10-31 | — | — | CN | disclosed |
| US-20170283438-A1 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-05 | — | — | US | disclosed |
| EP-3209651-A1 | CARBAZOLE DERIVATIVES | Bristol-Myers Squibb Company (US) | 2017-08-30 | — | — | EP | disclosed |
| EP-3209652-A1 | TRICYCLIC ATROPISOMER COMPOUNDS | Bristol-Myers Squibb Company (US) | 2017-08-30 | — | — | EP | disclosed |
| CN-107108555-A | Three ring atropisomer compounds | 百时美施贵宝公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-107090456-A | The connection albumen led using the mediated rnai of short interfering nucleic acid（Cadherin related protein matter）, the suppression of the gene expressions of β 1 | 瑟纳治疗公司 | 2017-08-25 | — | — | CN | disclosed |
| CN-107074804-A | Carbazole derivates | 百时美施贵宝公司 | 2017-08-18 | — | — | CN | disclosed |
| US-9714234-B2 | Carbazole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| US-9714234-B2 | Carbazole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| EP-3013814-B1 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-06-14 | — | — | EP | disclosed |
| CN-106795151-A | Protein kinase C inhibitors and methods of their use | 诺华股份有限公司 | 2017-05-31 | — | — | CN | disclosed |
| EP-3013815-B1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-03 | — | — | EP | disclosed |
| WO-2017064317-A1 | NEW COMBINATION THERAPIES FOR TREATING NEUROLOGICAL DAMAGE | UNIVERSITAT AUTONOMA DE BARCELONA (ES) | 2017-04-20 | — | — | WO | disclosed |
| US-20170096426-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | THE UNIV OF MONTANA (US) | 2017-04-06 | — | — | US | disclosed |
| CN-106543070-A | Carbazole amide-type room temperature phosphorimetry molecule that N replaces and its preparation method and application | 武汉大学 | 2017-03-29 | — | — | CN | disclosed |
| CN-105073746-B | Substituted imidazopyridines as HDM2 inhibitors | 默沙东公司 | 2017-03-22 | — | — | CN | disclosed |
| EP-2838898-B1 | SUBSTITUTED HETERO-BICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | ADVINUS THERAPEUTICS LTD (IN) | 2017-01-18 | — | — | EP | disclosed |
| CN-103946223-B | 3-cyanaryl-1h-pyrazolo[2.3-b]pyridine derivatives | 默克专利股份公司 | 2017-01-18 | — | — | CN | disclosed |
| CN-103596938-B | Thiazole | 默克专利有限公司 | 2016-12-28 | — | — | CN | disclosed |
| CN-106008460-A | Pharmaceutically acceptable salts of 2-{4-[(3S)-piperidin-3- yl]phenyl} -2H-indazole-7-carboxamide | 默沙东有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-104093722-B | Furo [3,2-b]-and thieno [3,2-b] pyridine derivate as TBK1 and IKK inhibitor | 默克专利股份公司 | 2016-07-27 | — | — | CN | disclosed |
| US-20160200710-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2016-07-14 | — | — | US | disclosed |
| EP-3042903-A1 | Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof | Advinus Therapeutics Limited (IN) | 2016-07-13 | — | — | EP | disclosed |
| US-20160194338-A1 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLES CARBOXAMIDE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2016-07-07 | — | — | US | disclosed |
| CN-105732617-A | 7-azaindole derivatives | 默克专利股份公司 | 2016-07-06 | — | — | CN | disclosed |
| CN-105712991-A | 7-AZAINDOLE DERIVATIVES | 默克专利股份公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-103717600-B | Pyridopyrimidine derivatives | 默克专利股份公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-103748086-B | Pyridine and pyrazines derivatives | MERCK PATENT GMBH (DE) | 2016-05-25 | — | — | CN | disclosed |
| US-9334290-B2 | Substituted tetrahydrocarbazole and carbazole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-05-10 | — | — | US | disclosed |
| US-9334290-B2 | Substituted tetrahydrocarbazole and carbazole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-05-10 | — | — | US | disclosed |
| EP-3013815-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2016-05-04 | — | — | EP | disclosed |
| EP-3013814-A1 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2016-05-04 | — | — | EP | disclosed |
| CN-105473573-A | Carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2016-04-06 | — | — | CN | disclosed |
| CN-105473573-A | Carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2016-04-06 | — | — | CN | disclosed |
| CN-103052633-B | The indazole derivatives that amide group replaces is birdsed of the same feather flock together (ADP-ribose) AG14361 | BETTA PHARMACEUTICALS Co.,Ltd. (CN) | 2016-03-23 | — | — | CN | disclosed |
| CN-103189378-B | As the Pyrazolopyridine ketone derivatives of LPA receptor antagonist | MERCK PATENT GMBH (DE) | 2016-03-02 | — | — | CN | disclosed |
| CN-105358546-A | Substituted tetrahydrocarbazole and carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2016-02-24 | — | — | CN | disclosed |
| CN-105358546-A | Substituted tetrahydrocarbazole and carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2016-02-24 | — | — | CN | disclosed |
| CN-103502247-B | 7-azaindole derivatives | MERCK PATENT GMBH (DE) | 2016-02-24 | — | — | CN | disclosed |
| CN-103391938-B | Pyrido [2,3-B] pyrazines derivatives and therepic use thereof | MERCK PATENT GMBH (DE) | 2016-02-24 | — | — | CN | disclosed |
| CN-103403005-B | 5- ([1,2,3] -triazol-4-yl) -7H-pyrrolo [2,3-d ] pyrimidine derivatives | MERCK PATENT GMBH (DE) | 2016-02-03 | — | — | CN | disclosed |
| CN-105307656-A | Quinoline inhibitors of macrophage stimulating 1 receptor MST1R | MERCK PATENT GMBH | 2016-02-03 | — | — | CN | disclosed |
| EP-2582668-B1 | CARBOLINE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-01-13 | — | — | EP | disclosed |
| CN-103694258-B | For suppressing 1,3,4-thiadiazoles derivative of the spiral shell condensation of KSP kinesin activity | SCHERING CORPORATION (US) | 2016-01-13 | — | — | CN | disclosed |
| US-9233983-B2 | Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2016-01-12 | — | — | US | disclosed |
| EP-2961747-A1 | CARBAZOLE COMPOUNDS USEFUL AS BROMODOMAIN INHIBITORS | Bristol-Myers Squibb Company (US) | 2016-01-06 | — | — | EP | disclosed |
| WO-2014210085-A9 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-12-23 | — | — | WO | disclosed |
| US-9206156-B2 | Substituted indole derivatives | Grünenthal GmbH (DE) | 2015-12-08 | — | — | US | disclosed |
| CN-102666538-B | Pyrrolopyridinylpyri-idin-idin 2-ylamine derivatives | MERCK PATENT GMBH (DE) | 2015-11-25 | — | — | CN | disclosed |
| CN-105073746-A | Substituted imidazopyridines as HDM2 inhibitors | MERCK SHARP & DOHME | 2015-11-18 | — | — | CN | disclosed |
| CN-105050598-A | Novel compounds as ERK inhibitors | MERCK SHARP & DOHME | 2015-11-11 | — | — | CN | disclosed |
| CN-103168042-B | 7-([1,2,3]-triazole-4-yl) pyrrolo-[2,3-b] pyrazines derivatives | MERCK PATENT GMBH (DE) | 2015-10-21 | — | — | CN | disclosed |
| CN-102391222-B | As the hydroxamic acid ester of therapeutical agent | PHARMACYCLICS INC. (US) | 2015-10-21 | — | — | CN | disclosed |
| CN-103180320-B | 1H-pyrrolo [2,3-b ] pyridine derivatives | MERCK PATENT GMBH (DE) | 2015-10-07 | — | — | CN | disclosed |
| CN-104945382-A | Substituted piperidines that increase p53 activity and uses thereof | SCHERING CORP | 2015-09-30 | — | — | CN | disclosed |
| CN-102480966-B | Fused heterocyclic compounds and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-09-16 | — | — | CN | disclosed |
| CN-102822171-B | As the benzo naphthyridines amine of autotaxin inhibitors | MERCK PATENT GMBH (DE) | 2015-09-02 | — | — | CN | disclosed |
| CN-103764651-B | Be applicable to the 7-7-azaindole derivatives of Therapeutic cancer disease | MERCK PATENT GMBH (DE) | 2015-08-19 | — | — | CN | disclosed |
| CN-102858767-B | As the aminopyrimidine of SYK inhibitor | MERCK SHARP & DOHME CORP. (US) | 2015-08-19 | — | — | CN | disclosed |
| CN-102638981-B | Substituted piperidines that increase p53 activity and uses thereof | SCHERING CORP | 2015-07-22 | — | — | CN | disclosed |
| CN-104736543-A | 7-azaindol-2,7-naphthyridine derivative for the treatment of tumors | MERCK PATENT GMBH | 2015-06-24 | — | — | CN | disclosed |
| CN-102459172-B | Tetracyclic compound | CHUGAI PHARMACEUTICAL CO LTD | 2015-06-24 | — | — | CN | disclosed |
| CN-102584679-B | Benzocarbazole acylamide compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2015-06-17 | — | — | CN | disclosed |
| CN-104662018-A | Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof | ADVINUS THERAPEUTICS LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-101679266-B | PIM kinase inhibitors and methods of their use | NOVARTIS AG | 2015-05-06 | — | — | CN | disclosed |
| WO-2015051766-A1 | AMIDS SUBSTITUTED INDAZOLE DERIVATIVEES AS PLOY (ADP-RIBOSE) POLYMERASE INHIBITORS | BETTA PHARMACEUTICALS CO., LTD (CN) | 2015-04-16 | — | — | WO | disclosed |
| CN-102712604-B | Sulfoxide derivatives for treating tumors | MERCK PATENT GMBH | 2015-04-08 | — | — | CN | disclosed |
| US-20150064196-A1 | Substituted Hetero-Bicyclic Compounds, Compositions and Medicinal Applications Thereof | IMPETIS BIOSCIENCES LIMITED (IN) | 2015-03-05 | — | — | US | disclosed |
| EP-2838898-A1 | SUBSTITUTED HETERO-BICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | Advinus Therapeutics Limited (IN) | 2015-02-25 | — | — | EP | disclosed |
| CN-102216299-B | 2, 5-diamino-substituted pyrido [4, 3-d] pyrimidines as autotaxin inhibitors | MERCK PATENT GMBH | 2015-02-11 | — | — | CN | disclosed |
| CN-102292339-B | Novel heterocyclic compounds as MetAP-2 inhibitors | MERCK PATENT GMBH | 2015-01-28 | — | — | CN | disclosed |
| WO-2014210085-A1 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-12-31 | — | — | WO | disclosed |
| WO-2014210087-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-12-31 | — | — | WO | disclosed |
| US-20140378475-A1 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY | 2014-12-25 | — | — | US | disclosed |
| CN-104245675-A | Cyclic amides as MetAP-2 inhibitors | MERCK PATENT GMBH | 2014-12-24 | — | — | CN | disclosed |
| CN-102272121-B | Polymorphic forms of 3- (1- {3- [5- (1-methyl-piperidin-4-ylmethoxy) -pyrimidin-2-yl ] -benzyl } -6-oxo-1, 6-dihydro-pyridazin-3-yl) -benzonitrile hydrochloride and processes for their preparation | MERCK PATENT GMBH | 2014-12-10 | — | — | CN | disclosed |
| CN-102666544-B | Pyrrolo[2,3-d]pyrazin-7-yl pyrimidine compounds | MERCK PATENT GMBH | 2014-11-26 | — | — | CN | disclosed |
| CN-104136410-A | CINNAMIC ACID HYDROXYAMIDES AS INHIBITORS OF HISTONE DEACETYLASE 8 | PHARMACYCLICS INC | 2014-11-05 | — | — | CN | disclosed |
| CN-102481361-B | Compositions and methods for treating cancer | MERCK SHARP & DOHME CORP. (US) | 2014-10-22 | — | — | CN | disclosed |
| CN-104098506-A | Preparation method and application of benzo[c] carbazole amide compound | UNIV EAST CHINA SCIENCE & TECH | 2014-10-15 | — | — | CN | disclosed |
| CN-104098506-A | Preparation method and application of benzo[c] carbazole amide compound | UNIV EAST CHINA SCIENCE & TECH | 2014-10-15 | — | — | CN | disclosed |
| CN-104098506-A | Preparation method and application of benzo[c] carbazole amide compound | UNIV EAST CHINA SCIENCE & TECH | 2014-10-15 | — | — | CN | disclosed |
| CN-104093722-A | Furo [3,2-b]-thieno and [3,2-b]pyridine derivatives as tbk1 and ikk inhibitors | MERCK PATENT GMBH | 2014-10-08 | — | — | CN | disclosed |
| CN-102325753-B | Carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2014-09-10 | — | — | CN | disclosed |
| CN-102325753-B | Carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2014-09-10 | — | — | CN | disclosed |
| WO-2014134267-A1 | CARBAZOLE COMPOUNDS USEFUL AS BROMODOMAIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-09-04 | — | — | WO | disclosed |
| WO-2014113932-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-07-31 | — | — | WO | disclosed |
| WO-2014113942-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-07-31 | — | — | WO | disclosed |
| CN-103946223-A | 3-cyanaryl-1h-pyrazolo[2.3-b]pyridine derivatives | MERCK PATENT GMBH | 2014-07-23 | — | — | CN | disclosed |
| CN-103930416-A | Benzonitrile derivatives as kinase inhibitors | MERCK PATENT GMBH | 2014-07-16 | — | — | CN | disclosed |
| CN-103917545-A | BTK inhibitors | MERCK SHARP & DOHME | 2014-07-09 | — | — | CN | disclosed |
| CN-102369186-B | Piperidine and piperazine derivatives as autotaxin inhibitors | MERCK PATENT GMBH | 2014-07-09 | — | — | CN | disclosed |
| CN-102414211-B | 3- ([1,2,3] triazol-4-yl) pyrrolo [2,3-b ] pyridine derivatives | MERCK PATENT GMBH | 2014-06-04 | — | — | CN | disclosed |
| CN-102365271-B | Heterocyclic compounds as autotaxin inhibitors | MERCK PATENT GMBH | 2014-05-14 | — | — | CN | disclosed |
| CN-103764651-A | 7-azaindole derivatives suitable for treatment of cancers | MERCK PATENT GMBH | 2014-04-30 | — | — | CN | disclosed |
| CN-103748086-A | Pyridine-and pyrazine derivatives | MERCK PATENT GMBH | 2014-04-23 | — | — | CN | disclosed |
| CN-102369195-B | Autotaxin inhibitors | MERCK PATENT GMBH | 2014-04-16 | — | — | CN | disclosed |
| CN-103694258-A | Spiro-condensed 1, 3, 4-thiadiazole derivatives for inhibiting ksp kinesin activity | SCHERING CORP | 2014-04-02 | — | — | CN | disclosed |
| CN-101754965-B | CSF-1R inhibitors, compositions, and methods of use | NOVARTIS AG | 2014-03-19 | — | — | CN | disclosed |
| CN-103619172-A | Aminopyrimidines as SYK inhibitors | MERCK SHARP & DOHME | 2014-03-05 | — | — | CN | disclosed |
| CN-102264729-B | Polymorphic forms of 6- (1-methyl-1H-pyrazol-4-yl) -2- {3- [5- (2-morpholin-4-yl-ethoxy) -pyrimidin-2-yl ] -benzyl } -2H-pyridazin-3-one dihydrogenphosphate and processes for their preparation | MERCK PATENT GMBH | 2014-03-05 | — | — | CN | disclosed |
| CN-102471317-B | Aminopyridine derivatives for treating tumors and inflammatory diseases | MERCK PATENT GMBH | 2014-02-26 | — | — | CN | disclosed |
| CN-103596938-A | Thiazole derivatives | MERCK PATENT GMBH | 2014-02-19 | — | — | CN | disclosed |
| CN-101903365-B | Spiro-condensed 1,3, 4-thiadiazole derivatives for inhibiting KSP kinesin activity | MERCK SHARP & DOHME | 2014-02-05 | — | — | CN | disclosed |
| CN-103502247-A | 7-azaindole derivatives | MERCK PATENT GMBH | 2014-01-08 | — | — | CN | disclosed |
| EP-2391602-B1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2013-12-04 | — | — | EP | disclosed |
| CN-103403005-A | 5- ([1,2,3] -triazol-4-yl) -7H-pyrrolo [2,3-d ] pyrimidine derivatives | MERCK PATENT GMBH | 2013-11-20 | — | — | CN | disclosed |
| CN-103391938-A | Pyrido [2, 3 - b] pyrazine derivatives and their therapeutical uses | MERCK PATENT GMBH | 2013-11-13 | — | — | CN | disclosed |
| CN-101679425-B | 6-(pyrrolopyridinyl)-pyrimidine-2-yl-amine and its uses in treating cancer and AIDS | MERCK PATENT GMBH | 2013-11-06 | — | — | CN | disclosed |
| CN-101855221-B | Pyridazinone derivatives as PARP inhibitors | ANGELETTI P IST RICHERCHE BIO | 2013-10-30 | — | — | CN | disclosed |
| WO-2013157022-A1 | SUBSTITUTED HETERO-BICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | ADVINUS THERAPEUTICS LIMITED (IN) | 2013-10-24 | — | — | WO | disclosed |
| WO-2013157021-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | ADVINUS THERAPEUTICS LIMITED (IN) | 2013-10-24 | — | — | WO | disclosed |
| CN-102056926-B | Pyrrolopyridinylpyrimidin-2-ylamine derivatives | MERCK PATENT GMBH | 2013-10-16 | — | — | CN | disclosed |
| CN-101600706-B | Inhibitors of akt activity | MERCK SHARP & DOHME | 2013-10-16 | — | — | CN | disclosed |
| CN-103282497-A | RNA interference-mediated suppression of Hepatitis B Virus (HBV) gene expression using short interfering nucleic acids (siNA) | MERCK SHARP & DOHME | 2013-09-04 | — | — | CN | disclosed |
| CN-101432281-B | 6-0-substituted benzoxazole and benzothiazole compounds and methods of inhibiting CSF-1R signaling | NOVARTIS AG | 2013-08-28 | — | — | CN | disclosed |
| CN-103228657-A | 3-heteroaryl-substituted pyrrolo [2,3-b ] pyridine derivatives as PDK1 inhibitors | MERCK PATENT GMBH | 2013-07-31 | — | — | CN | disclosed |
| CN-101578279-B | Amide substituted indazoles as poly (ADP ribose) polymerase (PARP) inhibitors | ANGELETTI P IST RICHERCHE BIO | 2013-07-17 | — | — | CN | disclosed |
| CN-101203495-B | Benzocycloheptapyridine compounds as inhibitors of receptor tyrosine kinase MET | MERCK SHARP & DOHME | 2013-07-17 | — | — | CN | disclosed |
| US-8486990-B2 | SirT inhibitors that bind to NAD | ELIXIR PHARMACEUTICALS, INC. (US) | 2013-07-16 | — | — | US | disclosed |
| CN-103189378-A | Pyrazolopyridinone derivatives as LPA receptor antagonists | MERCK PATENT GMBH | 2013-07-03 | — | — | CN | disclosed |
| CN-103180320-A | 1H-pyrrolo [2,3-b ] pyridine derivatives | MERCK PATENT GMBH | 2013-06-26 | — | — | CN | disclosed |
| CN-103168042-A | 7-((1,2,3)Triazol-4-yl)-pyrrolo(2,3) pyrazinderivate | MERCK PATENT GMBH | 2013-06-19 | — | — | CN | disclosed |
| US-20130116283-A1 | Substituted indole derivatives | Grünenthal GmbH (DE) | 2013-05-09 | — | — | US | disclosed |
| CN-103080093-A | Indazole compounds and their uses | DANA FARBER CANCER INST INC | 2013-05-01 | — | — | CN | disclosed |
| EP-2582668-A1 | CARBOLINE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2013-04-24 | — | — | EP | disclosed |
| CN-103068980-A | RNA interference mediated inhibition of the catenin (cadherin-associated protein), beta 1(CTNNB1) gene expression using short interfering nucleic acids (siNA) | MERCK SHARP & DOHME | 2013-04-24 | — | — | CN | disclosed |
| US-20130096118-A1 | CARBOLINE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2013-04-18 | — | — | US | disclosed |
| CN-103052633-A | Amids Substituted Indazole Derivativees As Ploy(adp-ribose)polymerase Inhibitors | ZHEJIANG BETA PHARMA INC | 2013-04-17 | — | — | CN | disclosed |
| CN-102971293-A | Bipyridine derivatives for the treatment of kinase-induced diseases | MERCK PATENT GMBH | 2013-03-13 | — | — | CN | disclosed |
| CN-101415686-B | Amide substituted indazole and benzotriazole derivatives as poly(ADP-ribose)polymerase (PARP) inhibitors | ANGELETTI P IST RICHERCHE BIO | 2013-03-13 | — | — | CN | disclosed |
| CN-102958930-A | 2,4- diaryl - substituted [1,8] naphthyridines as kinase inhibitors for use against cancer | MERCK PATENT GMBH | 2013-03-06 | — | — | CN | disclosed |
| US-8362065-B2 | Carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-01-29 | — | — | US | disclosed |
| US-8362065-B2 | Carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-01-29 | — | — | US | disclosed |
| CN-101374515-B | Inhibitors of akt activity | MERCK SHARP & DOHME | 2013-01-09 | — | — | CN | disclosed |
| CN-102858767-A | Aminopyrimidines as SYK inhibitors | MERCK SHARP & DOHME | 2013-01-02 | — | — | CN | disclosed |
| CN-102822171-A | Benzonaphthyridinamines as autotaxin inhibitors | MERCK PATENT GMBH | 2012-12-12 | — | — | CN | disclosed |
| CN-101253168-B | Substituted benzimidazoles as kinase inhibitors | NOVARTIS AG | 2012-12-12 | — | — | CN | disclosed |
| CN-101809001-B | Imidazole derivatives | MERCK PATENT GMBH | 2012-12-12 | — | — | CN | disclosed |
| CN-101535268-B | Tyrosine kinase inhibitors | MERCK SHARP & DOHME | 2012-11-14 | — | — | CN | disclosed |
| CN-102712604-A | Sulfoxide derivatives for treating tumors | MERCK PATENT GMBH | 2012-10-03 | — | — | CN | disclosed |
| CN-102666538-A | Pyrrolopyridinyl-pyrimidin-2-ylamine derivatives | MERCK PATENT GMBH | 2012-09-12 | — | — | CN | disclosed |
| CN-102666544-A | Pyrrolo[2,3-d]pyrazin-7-yl pyrimidine compounds | MERCK PATENT GMBH | 2012-09-12 | — | — | CN | disclosed |
| CN-102638981-A | Substituted piperidines that increase p53 activity and uses thereof | SCHERING CORP | 2012-08-15 | — | — | CN | disclosed |
| CN-102596200-A | Heteroarylaminoquinolines as tgf-beta receptor kinase inhibitors | MERCK PATENT GMBH | 2012-07-18 | — | — | CN | disclosed |
| CN-102584679-A | Benzocarbazole acylamide compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2012-07-18 | — | — | CN | disclosed |
| CN-102480966-A | Fused heterocyclic compounds and uses thereof | NOVARTIS AG | 2012-05-30 | — | — | CN | disclosed |
| CN-102481361-A | Compositions and methods for treating cancer | MERCK SHARP & DOHME | 2012-05-30 | — | — | CN | disclosed |
| CN-102471343-A | Heterocyclic compounds as autotaxin inhibitors | MERCK PATENT GMBH | 2012-05-23 | — | — | CN | disclosed |
| CN-102471317-A | Aminopyridine derivatives for treating tumors and inflammatory diseases | MERCK PATENT GMBH | 2012-05-23 | — | — | CN | disclosed |
| CN-102459172-A | Tetracyclic compounds | CHUGAI PHARMACEUTICAL CO LTD | 2012-05-16 | — | — | CN | disclosed |
| WO-2012040321-A3 | METHODS AND APPARATUS FOR EHNANCED GAS DISTRIBUTION | GRUPO PETROTEMEX, S.A. DE C.V. (MX) | 2012-05-10 | — | — | WO | disclosed |
| CN-102414211-A | 3- ([1,2,3] triazol-4-yl) pyrrolo [2,3-b ] pyridine derivatives | MERCK PATENT GMBH | 2012-04-11 | — | — | CN | disclosed |
| CN-102391222-A | Novel hydroxamates as therapeutic agents | PHARMACYCLICS INC | 2012-03-28 | — | — | CN | disclosed |
| CN-102370967-A | Novel application of IL-1Ra (interleukin-1 receptor antagonist) and tumor treatment medicinal composition kit thereof | UNIV SHANGHAI JIAOTONG | 2012-03-14 | — | — | CN | disclosed |
| US-20120058996-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2012-03-08 | — | — | US | disclosed |
| CN-102369186-A | Piperidine and piperazine derivatives as autotaxin inhibitors | MERCK PATENT GMBH | 2012-03-07 | — | — | CN | disclosed |
| CN-102369195-A | Autotaxin inhibitors | MERCK PATENT GMBH | 2012-03-07 | — | — | CN | disclosed |
| CN-102365271-A | Heterocyclic compounds as autotaxin inhibitors | MERCK PATENT GMBH | 2012-02-29 | — | — | CN | disclosed |
| US-20120039804-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-16 | — | — | US | disclosed |
| CN-102325753-A | Carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2012-01-18 | — | — | CN | disclosed |
| US-8084620-B2 | Carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-12-27 | — | — | US | disclosed |
| US-8084620-B2 | Carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-12-27 | — | — | US | disclosed |
| WO-2011159857-A1 | CARBOLINE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-12-22 | — | — | WO | disclosed |
| CN-102292339-A | Novel heterocyclic compounds as MetAP-2 inhibitors | — | 2011-12-21 | — | — | CN | disclosed |
| EP-1981881-B1 | TETRAHYDROPYRANE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-12-07 | — | — | EP | disclosed |
| CN-102272121-A | Novel polymorphic forms of 3- (1- {3- [5- (1-methyl-piperidin-4-ylmethoxy) -pyrimidin-2-yl ] -benzyl } -6-oxo-1, 6-dihydro-pyridazin-3-yl) -benzonitrile hydrochloride and processes for their preparation | — | 2011-12-07 | — | — | CN | disclosed |
| EP-2391602-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2011-12-07 | — | — | EP | disclosed |
| CN-101346383-B | Triazole derivatives | MERCK PATENT GMBH (DE) | 2011-11-30 | — | — | CN | disclosed |
| CN-102264729-A | New polymorphic form of 6- (1-methyl-1H-pyrazol-4-yl) -2- {3- [5- (2-morpholin-4-yl-ethoxy) -pyrimidin-2-yl ] -benzyl } -2H-pyridazin-3-one dihydrogenphosphate and process for preparing same | — | 2011-11-30 | — | — | CN | disclosed |
| CN-102227426-A | Benzonaphtyridine compounds used as inhibitors of autotaxin | MERCK PATENT GMBH | 2011-10-26 | — | — | CN | disclosed |
| CN-102216299-A | 2, 5-diamino-substituted pyrido [4, 3-d] pyrimidines as autotaxin inhibitors against cancer | MERCK PATENT GMBH | 2011-10-12 | — | — | CN | disclosed |
| CN-101115742-B | Heterocycle derivatives as histone deacetylase (hdac) inhibitors | ANGELETTI P IST RICHERCHE BIO | 2011-06-22 | — | — | CN | disclosed |
| CN-102056926-A | Pyrrolopyridinylpyrimidin-2-ylamine derivatives | MERCK PATENT GMBH | 2011-05-11 | — | — | CN | disclosed |
| CN-102015724-A | Thienopyrimidines | MERCK PATENT GMBH | 2011-04-13 | — | — | CN | disclosed |
| CN-102017525-A | Inhibitors of checkpoint kinases | MERCK & CO INC | 2011-04-13 | — | — | CN | disclosed |
| CN-102010416-A | Substituted tetrahydroquinolines | MERCK PATENT GMBH | 2011-04-13 | — | — | CN | disclosed |
| CN-102014631-A | Tyrosine kinase inhibitors | TIGER PHARMATECH | 2011-04-13 | — | — | CN | disclosed |
| CN-102014902-A | Inhibitors of checkpoint kinases | MERCK & CO INC | 2011-04-13 | — | — | CN | disclosed |
| CN-101155583-B | Mitotic kinesin inhibitors | MERCK SHARP & DOHME | 2011-01-19 | — | — | CN | disclosed |
| CN-101952255-A | Compounds for inhibiting KSP kinesin activity | SCHERING CORP | 2011-01-19 | — | — | CN | disclosed |
| CN-101932572-A | Pharmaceutically acceptable salts of 2- {4- [ (3S) -piperidin-3-yl ] phenyl } -2H-indazole-7-carboxamide | MERCK & CO INC | 2010-12-29 | — | — | CN | disclosed |
| CN-101918404-A | 4-(pyrrolo[2,3-c]pyridine-3-yl)-pyrimidine-2-amine derivatives | MERCK PATENT GMBH | 2010-12-15 | — | — | CN | disclosed |
| CN-101903343-A | Be used to suppress the active compound of KSP kinesin | SCHERING CORP | 2010-12-01 | — | — | CN | disclosed |
| CN-101903395-A | Compounds for inhibiting KSP kinesin activity | SCHERING CORP | 2010-12-01 | — | — | CN | disclosed |
| CN-101903365-A | Spiro-condensed 1,3, 4-thiadiazole derivatives for inhibiting KSP kinesin activity | SCHERING CORP | 2010-12-01 | — | — | CN | disclosed |
| CN-1980938-B | Mitotic kinesin inhibitors | MERCK & CO INC | 2010-11-03 | — | — | CN | disclosed |
| CN-1953768-B | Highly concentrated liquid formulations of anti-EGFR antibodies | MERCK PATENT GMBH | 2010-10-13 | — | — | CN | disclosed |
| CN-101855221-A | Pyridazinone derivatives as PARP inhibitors | ANGELETTI P IST RICHERCHE BIO | 2010-10-06 | — | — | CN | disclosed |
| US-20100227896-A1 | USE OF VITAMIN PP COMPOUNDS | ASTELLAS DEUTSCHLAND GMBH (DE) | 2010-09-09 | — | — | US | disclosed |
| CN-101827851-A | 5-cyano-thienopyridines for the treatment of tumors | MERCK PATENT GMBH | 2010-09-08 | — | — | CN | disclosed |
| CN-101815714-A | Thiazol derivatives | MERCK PATENT GMBH | 2010-08-25 | — | — | CN | disclosed |
| CN-101809001-A | Imdazole derivatives | MERCK PATENT GMBH | 2010-08-18 | — | — | CN | disclosed |
| CN-101808518-A | Pyridyl and pyrimidinyl derivatives as histone deacetylase inhibitors | MERCK & CO INC | 2010-08-18 | — | — | CN | disclosed |
| CN-101808988-A | Piperidine and piperazine derivatives | MERCK PATENT GMBH | 2010-08-18 | — | — | CN | disclosed |
| CN-101801379-A | CSF-1R inhibitors for treatment of cancer and bone diseases | NOVARTIS AG | 2010-08-11 | — | — | CN | disclosed |
| WO-2010080481-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-07-15 | — | — | WO | disclosed |
| US-20100160303-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2010-06-24 | — | — | US | disclosed |
| CN-101754965-A | CSF-1R inhibitors, compositions, and methods of use | NOVARTIS AG | 2010-06-23 | — | — | CN | disclosed |
| CN-101679372-A | Solid forms of a RAF kinase inhibitor | NOVARTIS AG | 2010-03-24 | — | — | CN | disclosed |
| CN-101679266-A | PIM kinase inhibitors and methods of their use | NOVARTIS AG | 2010-03-24 | — | — | CN | disclosed |
| CN-101679425-A | 6-(pyrrolopyridinyl)-pyrimidine-2-yl-amine derivatives | MERCK PATENT GMBH | 2010-03-24 | — | — | CN | disclosed |
| CN-101641362-A | Substituted tetrahydroquinolines | MERCK PATENT GMBH DE | 2010-02-03 | — | — | CN | disclosed |
| CN-101636401-A | Tetrahydroquinoline derivatives and their use for the treatment of cancer | MERCK PATENT GMBH | 2010-01-27 | — | — | CN | disclosed |
| CN-101616918-A | 4- (pyrrolopyridinyl) pyrimidin-2-ylamine derivatives | MERCK PATENT GMBH | 2009-12-30 | — | — | CN | disclosed |
| CN-101600706-A | Inhibitors of AKT activity | MERCK & CO INC (US) | 2009-12-09 | — | — | CN | disclosed |
| CN-101578279-A | Amide substituted indazoles as poly (ADP ribose) polymerase (PARP) inhibitors | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-11-11 | — | — | CN | disclosed |
| CN-100549006-C | The mitotic kinesins inhibitor | MERCK & CO INC (US) | 2009-10-14 | — | — | CN | disclosed |
| CN-100548296-C | The mitotic kinesins inhibitor | MERCK & CO INC (US) | 2009-10-14 | — | — | CN | disclosed |
| CN-101535268-A | Tyrosine kinase inhibitors | MERCK & CO INC (US) | 2009-09-16 | — | — | CN | disclosed |
| US-20090215828-A1 | Substituted indole derivatives | GRUNENTHAL GMBH (DE) | 2009-08-27 | — | — | US | disclosed |
| CN-101500613-A | A novel lactic acid formulation of MK-0457 useful for the treatment of cancer | MERCK & CO INC (US) | 2009-08-05 | — | — | CN | disclosed |
| CN-101432281-A | 6-O-substituted benzoxazole and benzothiazole compounds and methods for inhibiting CSF-1R signaling | NOVARTIS AG (CH) | 2009-05-13 | — | — | CN | disclosed |
| CN-101415686-A | Amide substituted indazole and benzotriazole derivatives as poly(ADP-ribose)polymerase (PARP) inhibitors | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-04-22 | — | — | CN | disclosed |
| CN-101374515-A | Inhibitors of AKT activity | MERCK & CO INC (US) | 2009-02-25 | — | — | CN | disclosed |
| CN-100457728-C | Tyrosine kinase inhibitors | MERCK & CO INC (US) | 2009-02-04 | — | — | CN | disclosed |
| CN-101346383-A | Triazole derivatives | MERCK PATENT GMBH (DE) | 2009-01-14 | — | — | CN | disclosed |
| CN-101341151-A | Diazepinones | MERCK PATENT GMBH (DE) | 2009-01-07 | — | — | CN | disclosed |
| CN-101312976-A | Spirocyclic compounds as hdac inhibitors | MERCK & CO INC (US) | 2008-11-26 | — | — | CN | disclosed |
| WO-2008141189-A1 | GHRELIN MODULATING COMPOUNDS AND COMBINATIONS THEREOF | ELIXIR PHARMACEUTICALS, INC. (US) | 2008-11-20 | — | — | WO | disclosed |
| CN-100422158-C | Inhibitors of Akt activity | MERCK & CO INC (US) | 2008-10-01 | — | — | CN | disclosed |
| CN-100421665-C | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2008-10-01 | — | — | CN | disclosed |
| CN-101263124-A | Quinazoline derivatives useful in cancer treatment | SCHERING CORP (US) | 2008-09-10 | — | — | CN | disclosed |
| CN-101263125-A | Quinazoline derivatives useful in cancer treatment | SCHERING CORP (US) | 2008-09-10 | — | — | CN | disclosed |
| CN-101257924-A | Formulation and method for enhancement of gastrointestinal absorption of pharmaceutical agents | WARNER LAMBERT CO (US) | 2008-09-03 | — | — | CN | disclosed |
| CN-101253168-A | Substituted benzimidazoles as kinase inhibitors | NOVARTIS AG (CH) | 2008-08-27 | — | — | CN | disclosed |
| CN-101242834-A | Inhibitors of AKT activity | MERCK & CO INC (US) | 2008-08-13 | — | — | CN | disclosed |
| EP-1951252-A2 | TYROSINE KINASE INHIBITORS | Merck & Co., Inc. (US) | 2008-08-06 | — | — | EP | disclosed |
| CN-100403900-C | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2008-07-23 | — | — | CN | disclosed |
| CN-101217958-A | Inhibitors of AKT activity | MERCK & CO INC (US) | 2008-07-09 | — | — | CN | disclosed |
| CN-101203495-A | Benzocycloheptapyridine compounds as inhibitors of receptor tyrosine kinase MET | MERCK & CO INC (US) | 2008-06-18 | — | — | CN | disclosed |
| CN-101198613-A | Substituted tetrahydroquinolines | MERCK PATENT GMBH (DE) | 2008-06-11 | — | — | CN | disclosed |
| CN-101193637-A | Fluorinated aminoalkyl-4-oxo-3, 4-dihydropyrido [3, 4-d ] pyrimidine compounds as mitotic kinesin inhibitors | MERCK & CO INC (US) | 2008-06-04 | — | — | CN | disclosed |
| CN-101171254-A | Fused thieno[2,3-B]pyridine and thiazolo[5,4-B]pyridine compounds for inhibiting KSP kinesin activity | SCHERING CORP (US) | 2008-04-30 | — | — | CN | disclosed |
| CN-101171052-A | Compounds that inhibit KSP kinesin activity | SCHERING CORP (US) | 2008-04-30 | — | — | CN | disclosed |
| CN-101163690-A | Benzothiophene hydroxamic acid derivatives | MERCK & CO INC (US) | 2008-04-16 | — | — | CN | disclosed |
| CN-101163471-A | Benzothiophene hydroxamic acid derivatives with carbamate, urea, amide and sulfonamide substitutions | MERCK & CO INC (US) | 2008-04-16 | — | — | CN | disclosed |
| CN-101155588-A | Inhibitors of akt activity | MERCK & CO INC (US) | 2008-04-02 | — | — | CN | disclosed |
| CN-101155583-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2008-04-02 | — | — | CN | disclosed |
| CN-101142183-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2008-03-12 | — | — | CN | disclosed |
| CN-101137372-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2008-03-05 | — | — | CN | disclosed |
| EP-1893607-A2 | INHIBITORS OF CHECKPOINT KINASES | Merck & Co., Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| CN-101133024-A | Amide derivatives as histone deacetylase inhibitors | ANGELETTI P IST RICHERCHE BIO (IT) | 2008-02-27 | — | — | CN | disclosed |
| CN-101115742-A | Heterocycle derivatives as histone deacetylase (hdac) inhibitors | ANGELETTI P IST RICHERCHE BIO (IT) | 2008-01-30 | — | — | CN | disclosed |
| CN-101115724-A | Inhibitors of checkpoint kinases | MERCK & CO INC (US) | 2008-01-30 | — | — | CN | disclosed |
| CN-101115479-A | Inhibitors of akt activity | MERCK & CO INC (US) | 2008-01-30 | — | — | CN | disclosed |
| CN-101115745-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2008-01-30 | — | — | CN | disclosed |
| CN-101107220-A | Amide derivatives as inhibitors of histone deacetylase | ANGELETTI P INST RICHERCHE BIO (IT) | 2008-01-16 | — | — | CN | disclosed |
| CN-101106998-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2008-01-16 | — | — | CN | disclosed |
| CN-101107253-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2008-01-16 | — | — | CN | disclosed |
| EP-1804786-A4 | SUBSTITUTED N-ARYL-9-OXO-9H-FLUORENE-1-CARBOXAMIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS | CYTOVIA INC (US) | 2008-01-02 | — | — | EP | disclosed |
| CN-101084194-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2007-12-05 | — | — | CN | disclosed |
| CN-101076335-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2007-11-21 | — | — | CN | disclosed |
| CN-101068811-A | Inhibitors of AKT activity | MERCK & CO INC (US) | 2007-11-07 | — | — | CN | disclosed |
| CN-101039932-A | Heterocyclic substituted bisarylurea derivatives as kinase inhibitors | MERCK PATENT GMBH (DE) | 2007-09-19 | — | — | CN | disclosed |
| CN-101018547-A | Histone deacetylase inhibitors | MERCK & CO INC (US) | 2007-08-15 | — | — | CN | disclosed |
| CN-101005837-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2007-07-25 | — | — | CN | disclosed |
| EP-1804786-A2 | SUBSTITUTED N-ARYL-9-OXO-9H-FLUORENE-1-CARBOXAMIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS | Cytovia, Inc. (US) | 2007-07-11 | — | — | EP | disclosed |
| CN-1997627-A | Histone deacetylase inhibitors | MERCK & CO INC (US) | 2007-07-11 | — | — | CN | disclosed |
| CN-1997626-A | Inhibitors of histone deacetylase | MERCK & CO INC (US) | 2007-07-11 | — | — | CN | disclosed |
| CN-1997625-A | Histone deacetylase inhibitors | MERCK & CO INC (US) | 2007-07-11 | — | — | CN | disclosed |
| CN-1980662-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2007-06-13 | — | — | CN | disclosed |
| CN-1980911-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2007-06-13 | — | — | CN | disclosed |
| CN-1980663-A | Prodrugs of mitotic kinesin inhibitors | MERCK & CO INC (US) | 2007-06-13 | — | — | CN | disclosed |
| CN-1980938-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2007-06-13 | — | — | CN | disclosed |
| WO-2007050383-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2007-05-03 | — | — | WO | disclosed |
| CN-1953768-A | Highly concentrated liquid formulations of anti-EGFR antibodies | MERCK PATENT GMBH (DE) | 2007-04-25 | — | — | CN | disclosed |
| CN-1942470-A | Inhibitors of AKT activity | MERCK & CO INC (US) | 2007-04-04 | — | — | CN | disclosed |
| CN-1942465-A | Inhibitors of AKT activity | MERCK & CO INC (US) | 2007-04-04 | — | — | CN | disclosed |
| CN-1934066-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2007-03-21 | — | — | CN | disclosed |
| CN-1898215-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2007-01-17 | — | — | CN | disclosed |
| CN-1898249-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2007-01-17 | — | — | CN | disclosed |
| WO-2007005676-A2 | ACTIVATOR COMPOSITIONS AND THEIR USE IN CATALYSTS AND OLEFIN POLYMERIZATION | ALBEMARLE CORPORATION (US) | 2007-01-11 | — | — | WO | disclosed |
| CN-1893951-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2007-01-10 | — | — | CN | disclosed |
| CN-1886118-A | Solid forms of anti-EGFR antibodies | MERCK PATENT GMBH (DE) | 2006-12-27 | — | — | CN | disclosed |
| WO-2006135604-A2 | INHIBITORS OF CHECKPOINT KINASES | MERCK & CO., INC. (US) | 2006-12-21 | — | — | WO | disclosed |
| CN-1882571-A | Pyrrolderivate | MERCK PATENT GMBH (DE) | 2006-12-20 | — | — | CN | disclosed |
| CN-1875023-A | Use of thienopyrimidines | MERCK PATENT GMBH (DE) | 2006-12-06 | — | — | CN | disclosed |
| CN-1871232-A | Benzimidazolyl derivatives | MERCK PATENT GMBH (DE) | 2006-11-29 | — | — | CN | disclosed |
| CN-1839128-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2006-09-27 | — | — | CN | disclosed |
| CN-1835749-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2006-09-20 | — | — | CN | disclosed |
| CN-1835746-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2006-09-20 | — | — | CN | disclosed |
| CN-1835756-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2006-09-20 | — | — | CN | disclosed |
| CN-1829507-A | Tyrosine kinase inhibitors | MERCK & CO INC (US) | 2006-09-06 | — | — | CN | disclosed |
| CN-1826317-A | Tyrosine kinase inhibitors | MERCK & CO INC (US) | 2006-08-30 | — | — | CN | disclosed |
| CN-1809536-A | Inhibitors of Akt activity | MERCK & CO INC (US) | 2006-07-26 | — | — | CN | disclosed |
| CN-1809354-A | Inhibitors of Akt activity | MERCK & CO INC (US) | 2006-07-26 | — | — | CN | disclosed |
| CN-1809540-A | Inhibitors of Akt activity | MERCK & CO INC (US) | 2006-07-26 | — | — | CN | disclosed |
| CN-1809351-A | Inhibitors of Akt activity | MERCK & CO INC (US) | 2006-07-26 | — | — | CN | disclosed |
| CN-1805686-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2006-07-19 | — | — | CN | disclosed |
| CN-1805928-A | Prodrugs of mitotic kinesin inhibitors | MERCK & CO INC (US) | 2006-07-19 | — | — | CN | disclosed |
| CN-1795175-A | Acetylene derivatives as inhibitors of histone deacetylase | AXYS PHARM INC (US) | 2006-06-28 | — | — | CN | disclosed |
| CN-1768031-A | hydroxamates as therapeutic agents | AXYS PHARM INC (US) | 2006-05-03 | — | — | CN | disclosed |
| EP-1044197-B1 | PIPERIDINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKYNE CARBOXAMIDES AS CYTOSTATIC AGENTS AND IMMUNOSUPPRESSANTS | ASTELLAS PHARMA GMBH (DE) | 2006-04-19 | — | — | EP | disclosed |
| WO-2006039356-A2 | SUBSTITUTED N-ARYL-9-OXO-9H-FLUORENE-1-CARBOXAMIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS | CYTOVIA, INC. (US) | 2006-04-13 | — | — | WO | disclosed |
| US-20060074124-A1 | Methods of treating a disorder | IPSOL AG (LI) | 2006-04-06 | — | — | US | disclosed |
| EP-1599202-A1 | TETRACYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Pharmacia Italia S.p.A. (IT) | 2005-11-30 | — | — | EP | disclosed |
| EP-1079832-B1 | USE OF VITAMIN PP COMPOUNDS | KLINGE CO CHEM PHARM FAB (DE) | 2005-11-30 | — | — | EP | disclosed |
| CN-1674906-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2005-09-28 | — | — | CN | disclosed |
| EP-1572239-A1 | METHOD OF USING A COX-2 INHIBITOR AND A TOPOISOMERASE II INHIBITOR AS A COMBINATION THERAPY IN THE TREATMENT OF NEOPLASIA | Pharmacia Corporation (US) | 2005-09-14 | — | — | EP | disclosed |
| CN-1213045-C | Tyrosine kinase inhibitors | MERCK & CO INC (US) | 2005-08-03 | — | — | CN | disclosed |
| WO-2004071507-A1 | TETRACYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PHARMACIA ITALIA S.P.A. (IT) | 2004-08-26 | — | — | WO | disclosed |
| WO-2004058302-A1 | METHOD OF USING A COX-2 INHIBITOR AND A TOPOISOMERASE II INHIBITOR AS A COMBINATION THERAPY IN THE TREATMENT OF NEOPLASIA | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |
| WO-2004004727-A1 | 3,4-DIHYDROISOQUINOLIN-1-ONE DERIVATIVES AS INDUCERS OF APOPTOSIS | AXYS PHARMACEUTICALS, INC. (US) | 2004-01-15 | — | — | WO | disclosed |
| EP-1349836-A2 | TETRACYCLIC DERIVATIVES AS SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-10-08 | — | — | EP | disclosed |
| US-6593344-B1 | These substances have especially high cytostatic activities and pronounced immunosuppressive properties which make them suitable for therapeutic treatment in broad tumor spectrum and autoimmune diseases | KLINGE PHARMA GMBH (DE) | 2003-07-15 | — | — | US | disclosed |
| EP-0882726-B1 | Carbazol-carboxamides as 5-HT1F agonists | LILLY CO ELI (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6548703-B1 | Toning agent | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2003-04-15 | — | — | US | disclosed |
| CN-1409708-A | Tyrosine kinase inhibitors | MERCK & CO INC (US) | 2003-04-09 | — | — | CN | disclosed |
| CN-1390215-A | Tyrosine kinase inhibitors | MERCK & CO INC (US) | 2003-01-08 | — | — | CN | disclosed |
| WO-2002050029-A2 | TETRACYCLIC DERIVATIVES AS SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-06-27 | — | — | WO | disclosed |
| US-6399631-B1 | 3-AMIDO OR 3-SULFONAMIDO; EATING DISORDERS IN HUMANS, DOGS AND CATS | PFIZER INC. | 2002-06-04 | — | — | US | disclosed |
| CN-1067686-C | Fused polycyclic heterocycle derivatives | EISAI CO LTD (JP) | 2001-06-27 | — | — | CN | disclosed |
| EP-1079832-A1 | USE OF VITAMIN PP COMPOUNDS | Klinge Pharma GmbH (DE) | 2001-03-07 | — | — | EP | disclosed |
| EP-1044197-A2 | NEW PIPERIDINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES | Klinge Pharma GmbH (DE) | 2000-10-18 | — | — | EP | disclosed |
| EP-1043364-A1 | TONING AGENT | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999053920-A1 | USE OF VITAMIN PP COMPOUNDS | KLINGE PHARMA GMBH (DE) | 1999-10-28 | — | — | WO | disclosed |
| US-5952335-A | ANTITUMOR AGENTS | EISAI CO., LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| WO-1999031060-A2 | PIPERIDINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES AS CYTOSTATICS AND IMMUNESUPPRESSANTS | KLINGE PHARMA GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |
| EP-0882726-A1 | Carbazol-carboxamides as 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-12-09 | — | — | EP | disclosed |
| CN-1185781-A | Fused Polycyclic Heterocyclic Derivatives | EISAI CO LTD (JP) | 1998-06-24 | — | — | CN | disclosed |
| US-4987153-A | ANTIEDEMIC, ANTIINFLAMMATORY | ROUSSEL UCLAF (FR) | 1991-01-22 | — | — | US | disclosed |
| US-4782075-A | ANTIINFLAMMATORY, ANTIEDEMIC | ROUSSEL UCLAF (FR) | 1988-11-01 | — | — | US | disclosed |
| US-3932456-A | VIRICIDES | RICHARDSON-MERRELL INC. (US) | 1976-01-13 | — | — | US | disclosed |
| US-3932456-A | VIRICIDES | RICHARDSON-MERRELL INC. (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (30 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215828-A1 | Substituted indole derivatives | IDO1, IDO2, TPH1 | PIM3 829/4885PIM1 1424/4885PBRM1 4365/4885 |
| US-20120058996-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BTK, FLT3, JAK1 | PIM3 102/4885PIM1 90/4885PBRM1 1307/4885 |
| US-20140378475-A1 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS | BTK, CNKSR1, JAK2 | PIM3 612/4885PIM1 920/4885PBRM1 777/4885 |
| US-20060074124-A1 | Methods of treating a disorder | CPT1B, CYP27A1, CLN6 | PIM3 4704/4885PIM1 4563/4885PBRM1 3003/4885 |
| US-20160200710-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS | BTK, CNKSR1, SYK | PIM3 374/4885PIM1 808/4885PBRM1 1785/4885 |
| US-20190161504-A1 | CARBENE COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | SCO2, CYCS, AOC2 | PIM3 734/4885PIM1 1129/4885PBRM1 2345/4885 |
| US-20170355673-A1 | TRICYCLIC ATROPISOMER COMPOUNDS | BTK, LCK, SYK | PIM3 3490/4885PIM1 3113/4885PBRM1 387/4885 |
| US-10266491-B2 | Carbazole derivatives | BTK, SYK, JAK2 | PIM3 619/4885PIM1 737/4885PBRM1 1894/4885 |
| US-10676434-B2 | Carbazole derivatives | BTK, SYK, JAK2 | PIM3 582/4885PIM1 762/4885PBRM1 2046/4885 |
| US-20120039804-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | CNR1, CNR2, OPRL1 | PIM3 4039/4885PIM1 4025/4885PBRM1 410/4885 |
| US-20230250111-A1 | CARBENE COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | CYCS, SCO2, UQCRB | PIM3 2627/4885PIM1 2211/4885PBRM1 2001/4885 |
| US-20100227896-A1 | USE OF VITAMIN PP COMPOUNDS | PNPO, NAMPT, NAPRT | PIM3 3370/4885PIM1 2734/4885PBRM1 1348/4885 |
| US-20100160303-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BTK, FLT3, JAK1 | PIM3 102/4885PIM1 90/4885PBRM1 1307/4885 |
| US-12180230-B2 | Carbene compounds and organic electroluminescent devices | SCO2, CYCS, AOC2 | PIM3 734/4885PIM1 1129/4885PBRM1 2345/4885 |
| US-20130096118-A1 | CARBOLINE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BTK, PRKACA, CILK1 | PIM3 159/4885PIM1 101/4885PBRM1 915/4885 |
| US-20180079758-A1 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS | BTK, CNKSR1, JAK2 | PIM3 612/4885PIM1 920/4885PBRM1 777/4885 |
| US-20170362176-A1 | CARBAZOLE DERIVATIVES | BTK, SYK, JAK2 | PIM3 619/4885PIM1 737/4885PBRM1 1894/4885 |
| US-20190023719-A1 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS | BTK, CNKSR1, JAK2 | PIM3 612/4885PIM1 920/4885PBRM1 777/4885 |
| US-20160194338-A1 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLES CARBOXAMIDE COMPOUNDS | BTK, CNKSR1, JAK2 | PIM3 726/4885PIM1 983/4885PBRM1 704/4885 |
| US-20130116283-A1 | Substituted indole derivatives | IDO1, IDO2, TPH1 | PIM3 829/4885PIM1 1424/4885PBRM1 4365/4885 |
| US-11053197-B2 | Carbazole derivatives | BTK, SYK, JAK2 | PIM3 582/4885PIM1 762/4885PBRM1 2046/4885 |
| US-12577261-B2 | Carbene compounds and organic electroluminescent devices | ZYX, CDYL, CTCF | PIM3 1910/4885PIM1 2262/4885PBRM1 2536/4885 |
| US-20190225583-A1 | CARBAZOLE DERIVATIVES | BTK, SYK, JAK2 | PIM3 582/4885PIM1 762/4885PBRM1 2046/4885 |
| US-20170096426-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | CNR1, CNR2, OPRL1 | PIM3 4039/4885PIM1 4025/4885PBRM1 410/4885 |
| US-10023534-B2 | Carbazole and tetrahydrocarbazole compounds useful as inhibitors of BTK | BTK, JAK2, SYK | PIM3 1283/4885PIM1 1201/4885PBRM1 1178/4885 |
| US-20170283438-A1 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS | BTK, CNKSR1, JAK2 | PIM3 612/4885PIM1 920/4885PBRM1 777/4885 |
| US-10106559-B2 | Substituted tetrahydrocarbazole and carbazole carboxamide compounds | BTK, CNKSR1, JAK2 | PIM3 612/4885PIM1 920/4885PBRM1 777/4885 |
| US-10435415-B2 | Substituted tetrahydrocarbazole and carbazole carboxamide compounds | BTK, CNKSR1, JAK2 | PIM3 612/4885PIM1 920/4885PBRM1 777/4885 |
| US-20200255377-A1 | CARBAZOLE DERIVATIVES | BTK, SYK, JAK2 | PIM3 582/4885PIM1 762/4885PBRM1 2046/4885 |
| US-20150064196-A1 | Substituted Hetero-Bicyclic Compounds, Compositions and Medicinal Applications Thereof | BTK, MALT1, LCK | PIM3 824/4885PIM1 291/4885PBRM1 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.