SCHEMBL6887279

SCHEMBL6887279

O=C(c1ccccc1C(=O)c1cccc2c1[nH]c1ccccc12)c1cccc2c1[nH]c1ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 2/20 0.58
KIF11 P52732 4/20 0.52
PIM3 Q86V86 2/20 0.50
PIM1 P11309 1/20 0.50
JAK2 O60674 1/20 0.50
TP53 P04637 1/20 0.50
MAPT P10636 1/20 0.50
HTT P42858 1/20 0.50
KLK7 P49862 1/20 0.50
PARP14 Q460N5 4/20 0.48
APP P05067 1/20 0.47
GPR84 Q9NQS5 1/20 0.47
MPL P40238 1/20 0.47
ALDH1A1 P00352 1/20 0.46
GPR3 P46089 1/20 0.46
HSD17B10 Q99714 1/20 0.46
GABRP O00591 1/20 0.46
GABRD O14764 1/20 0.46
GABRA1 P14867 1/20 0.46
GABRB1 P18505 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4654498 0.98 PBRM1 (0.60) PBRM1KIF11PIM3PIM1JAK2
SCHEMBL11801609 0.93 PBRM1 (0.65) PBRM1KIF11PIM3PIM1JAK2
SCHEMBL6887283 0.89 PBRM1 (0.55) PBRM1KIF11PIM3PIM1JAK2
SCHEMBL22371699 0.89 KIF11 (0.62) PBRM1KIF11PIM3PIM1JAK2
SCHEMBL30480324 0.89 KIF11 (0.62) PBRM1KIF11PIM3PIM1JAK2
SCHEMBL3910030 0.88 PBRM1 (0.58) PBRM1KIF11PIM3PIM1JAK2
SCHEMBL31485136 0.88 PBRM1 (0.58) PBRM1KIF11PIM3PIM1JAK2
SCHEMBL1515615 0.88 PBRM1 (0.54) PBRM1KIF11PIM3PIM1JAK2
SCHEMBL21763820 0.87 GPR84 (0.70) PBRM1PIM3PIM1TP53GPR84
SCHEMBL27623354 0.86 PBRM1 (0.53) PBRM1KIF11PIM3PIM1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472908-A1 WHITE LIGHT EMITTING OLEDS FROM COMBINED MONOMER AND AGGREGATE EMISSION THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2004-11-03 EP disclosed
WO-2003059015-A1 WHITE LIGHT EMITTING OLEDS FROM COMBINED MONOMER AND AGGREGATE EMISSION THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2003-07-17 WO disclosed