Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | EDNRB | P24530 | 4/20 | 0.42 |
| ▸ | EDNRA | P25101 | 4/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | MMP16 | P51512 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2445593 | 0.94 | PTGS2 (0.48) | ALOX5APFEN1ATRPTGS2CASP1 | |
| SCHEMBL28172581 | 0.80 | ALOX5AP (0.48) | ALOX5APFEN1ATRPTGS2EDNRA | |
| SCHEMBL28130041 | 0.79 | ALOX5AP (0.50) | ALOX5APFEN1ATR | |
| SCHEMBL2642960 | 0.79 | PTGS2 (0.47) | PTGS2CASP1EDNRBEDNRACDC25B | |
| SCHEMBL6904423 | 0.77 | OPRM1 (0.58) | ALOX5APFEN1PTGS2CASP1EDNRB | |
| SCHEMBL29415408 | 0.77 | PTGS2 (0.61) | PTGS2CASP1EDNRBEDNRAAKR1B1 | |
| SCHEMBL937206 | 0.77 | PTGS2 (0.61) | PTGS2CASP1EDNRBEDNRAAKR1B1 | |
| SCHEMBL31463127 | 0.76 | AKR1B1 (0.56) | PTGS2CASP1EDNRBEDNRACDC25A | |
| SCHEMBL28157438 | 0.76 | EDNRA (0.47) | ALOX5APFEN1ATREDNRBEDNRA | |
| SCHEMBL2705116 | 0.76 | ALOX5AP (0.50) | ALOX5APFEN1PTGS2CASP1EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103179976-A | Glucagon superfamily peptides exhibiting g protein-coupled receptor activity | MARCADIA BIOTECH INC | 2013-06-26 | — | — | CN | disclosed |