SCHEMBL6904423

SCHEMBL6904423

CC(C)N(C)S(=O)(=O)c1ccccc1-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.58
OPRK1 P41145 2/20 0.58
ALOX5AP P20292 3/20 0.48
FEN1 P39748 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.45
ALDH1A1 P00352 1/20 0.45
PTGS2 P35354 1/20 0.43
ADAMTS4 O75173 1/20 0.43
EDNRB P24530 4/20 0.42
EDNRA P25101 4/20 0.42
CASP1 P29466 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PDPK1 O15530 1/20 0.40
ROCK2 O75116 1/20 0.40
FES P07332 1/20 0.40
FER P16591 1/20 0.40
MARK3 P27448 1/20 0.40
FLT3 P36888 1/20 0.40
MAP4K2 Q12851 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9306541 0.85 ALOX5AP (0.57) OPRM1OPRK1ALOX5APFEN1SMN1; SMN2
SCHEMBL3221376 0.84 OPRM1 (0.54) OPRM1OPRK1ALOX5APFEN1SMN1; SMN2
SCHEMBL6698432 0.81 ALOX5AP (0.58) OPRM1OPRK1ALOX5APFEN1SMN1; SMN2
SCHEMBL15924549 0.81 ALOX5AP (0.44) OPRM1OPRK1ALOX5APFEN1SMN1; SMN2
SCHEMBL10782653 0.81 ALOX5AP (0.44) OPRM1OPRK1ALOX5APFEN1SMN1; SMN2
SCHEMBL3853249 0.80 MCOLN3 (0.57) OPRM1OPRK1ALOX5APFEN1PTGS2
SCHEMBL10957993 0.79 SMN1; SMN2 (0.46) OPRM1OPRK1ALOX5APFEN1SMN1; SMN2
SCHEMBL3204514 0.77 OPRK1 (0.70) OPRM1OPRK1ALDH1A1EDNRBEDNRA
SCHEMBL27907686 0.77 ALOX5AP (0.47) OPRM1OPRK1ALOX5APFEN1ALDH1A1
SCHEMBL9307372 0.76 ALOX5AP (0.52) ALOX5APFEN1SMN1; SMN2ALDH1A1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6828375-B2 Containing a thermoplastic elastomer grafted with maleic anhydride, carbon black powder, sulfonamide based material, and alkanedioic acid HYUNDAI MOTOR COMPANY (KR) 2004-12-07 US claimed
US-20020128373-A1 Electroconductive polyamide resin composition and molded product for motor component prepared therefrom HYUNDAI MOTOR COMPANY (KR) 2002-09-12 US claimed
US-6828375-B2 Containing a thermoplastic elastomer grafted with maleic anhydride, carbon black powder, sulfonamide based material, and alkanedioic acid HYUNDAI MOTOR COMPANY (KR) 2004-12-07 US disclosed
US-20020128373-A1 Electroconductive polyamide resin composition and molded product for motor component prepared therefrom HYUNDAI MOTOR COMPANY (KR) 2002-09-12 US disclosed