Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346472 | 0.86 | LMNA (0.44) | LMNAHSD17B10TSHRALOX15CYP3A4 | |
| SCHEMBL224525 | 0.81 | LMNA (0.52) | LMNAHSD17B10TSHRALOX15CYP3A4 | |
| Emylcamate SCHEMBL387718 | 0.80 | ALOX15 (0.42) | LMNAHSD17B10TSHRALOX15CYP3A4 | |
| SCHEMBL14991260 | 0.80 | LMNA (0.40) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL30552233 | 0.78 | LMNA (0.48) | LMNAHSD17B10TSHRALOX15CYP3A4 | |
| SCHEMBL12776904 | 0.78 | GAA (0.50) | LMNAHSD17B10TSHRTDP1FDPS | |
| SCHEMBL19925018 | 0.77 | LMNA (0.48) | LMNAHSD17B10TSHRALOX15CYP3A4 | |
| SCHEMBL28870458 | 0.77 | LMNA (0.48) | LMNAHSD17B10TSHRALOX15CYP3A4 | |
| SCHEMBL29063527 | 0.77 | LMNA (0.40) | LMNAHSD17B10TSHRALOX15CYP3A4 | |
| SCHEMBL1811804 | 0.77 | LMNA (0.40) | LMNAHSD17B10TSHRALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111153901-A | Nitrogen-containing fused heterocyclic SHP2 inhibitor compound, preparation method and application | 如东凌达生物医药科技有限公司 | 2020-05-15 | — | — | CN | disclosed |
| CN-102947267-A | Heterogeneously catalysed carbamate dissociation for synthesis of isocyanates over solid lewis acids | BASF SE | 2013-02-27 | — | — | CN | disclosed |