Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926052 | 0.84 | RIOK2 (0.63) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL27925926 | 0.82 | RAB9A (0.62) | KMT2AMEN1SMN1; SMN2POLBNPC1 | |
| SCHEMBL27907974 | 0.81 | WNT3A (0.60) | KMT2AMEN1SLC6A2SLC6A3RAB9A | |
| SCHEMBL27925939 | 0.80 | KMT2A (0.61) | GAAKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL27925932 | 0.79 | WNT3A (0.59) | KMT2AMEN1SLC6A2SLC6A3 | |
| SCHEMBL27907868 | 0.78 | KMT2A (0.55) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6245092 | 0.78 | GAA (1.00) | GAAKMT2AMEN1SLC6A2SLC6A3 | |
| SCHEMBL4908980 | 0.78 | KMT2A (0.82) | GAAKMT2AMEN1SLC6A2SLC6A3 | |
| SCHEMBL14324295 | 0.77 | NPC1 (0.59) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1430541 | 0.77 | GAA (0.76) | GAAKMT2AMEN1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103172636-A | Pyridine-quinazolinone compound and preparation method thereof | UNIV SHANGHAI | 2013-06-26 | — | — | CN | disclosed |