Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31351918 | 0.86 | KMT2A (0.61) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27925932 | 0.83 | WNT3A (0.59) | KMT2AMEN1 | |
| SCHEMBL27907982 | 0.80 | GAA (0.63) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22607250 | 0.80 | KMT2A (0.84) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27925926 | 0.80 | RAB9A (0.62) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16887483 | 0.77 | KMT2A (0.68) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL839206 | 0.76 | RAB9A (0.66) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5233630 | 0.75 | HCAR3 (0.56) | KMT2AMEN1NPC1ALDH1A1HSD17B10 | |
| SCHEMBL1723416 | 0.75 | RAB9A (0.68) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL838607 | 0.75 | RAB9A (0.68) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103172636-A | Pyridine-quinazolinone compound and preparation method thereof | UNIV SHANGHAI | 2013-06-26 | — | — | CN | disclosed |