Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27892442 | 0.89 | AOC3 (0.35) | HTR2CMCHR1KCNH2AOC3 | |
| SCHEMBL27909513 | 0.81 | HRH3 (0.43) | HRH3STK17B | |
| SCHEMBL27909499 | 0.80 | STK17B (0.36) | STK17B | |
| SCHEMBL27909504 | 0.80 | STK17B (0.36) | STK17B | |
| SCHEMBL27903328 | 0.79 | ALDH1A1 (0.42) | MCHR1 | |
| SCHEMBL23699622 | 0.76 | TYK2 (0.50) | STK17B | |
| SCHEMBL27909505 | 0.75 | IKBKB (0.32) | STK17B | |
| SCHEMBL27909503 | 0.75 | MAP4K4 (0.39) | STK17BKCNH2 | |
| SCHEMBL28805850 | 0.74 | CHEK1 (0.45) | MCHR1KCNH2 | |
| SCHEMBL28066464 | 0.73 | EGFR (0.43) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102971327-A | Anti-inflammatory compound having inhibitory activity against multiple tyrosine kinases, and pharmaceutical composition containing same | KOREA INST SCI & TECH | 2013-03-13 | — | — | CN | claimed |
| CN-102971327-B | There is the anti-inflammatory compound of multiple tyrosine-kinase enzyme inhibition activity and the pharmaceutical compositions containing these compounds | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-04-20 | — | — | CN | disclosed |
| CN-102971327-A | Anti-inflammatory compound having inhibitory activity against multiple tyrosine kinases, and pharmaceutical composition containing same | KOREA INST SCI & TECH | 2013-03-13 | — | — | CN | disclosed |