Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 7/20 | 0.34 |
| ▸ | FLT1 | P17948 | 6/20 | 0.34 |
| ▸ | KIT | P10721 | 3/20 | 0.34 |
| ▸ | NPR1 | P16066 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909496 | 0.89 | PRMT6 (0.38) | FLT1NPR1 | |
| SCHEMBL27909503 | 0.87 | MAP4K4 (0.39) | STK17BTYK2EGFRFLT1KIT | |
| SCHEMBL28066464 | 0.85 | EGFR (0.43) | EGFRFLT1CHEK1 | |
| SCHEMBL27909499 | 0.80 | STK17B (0.36) | STK17BTYK2EGFRKITNPC1 | |
| SCHEMBL27909497 | 0.80 | HRH3 (0.44) | STK17B | |
| SCHEMBL27892433 | 0.80 | EGFR (0.36) | STK17BEGFRFLT1NPR1SRC | |
| SCHEMBL27892401 | 0.77 | MAP4K4 (0.48) | NPR1NPC1RAB9A | |
| SCHEMBL27903328 | 0.76 | ALDH1A1 (0.42) | EGFRFLT1NPC1RAB9AKMT2A | |
| SCHEMBL23699622 | 0.76 | TYK2 (0.50) | STK17BTYK2KITNPC1RAB9A | |
| SCHEMBL27909505 | 0.75 | IKBKB (0.32) | STK17B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102971327-A | Anti-inflammatory compound having inhibitory activity against multiple tyrosine kinases, and pharmaceutical composition containing same | KOREA INST SCI & TECH | 2013-03-13 | — | — | CN | claimed |
| CN-102971327-B | There is the anti-inflammatory compound of multiple tyrosine-kinase enzyme inhibition activity and the pharmaceutical compositions containing these compounds | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-04-20 | — | — | CN | disclosed |
| CN-102971327-A | Anti-inflammatory compound having inhibitory activity against multiple tyrosine kinases, and pharmaceutical composition containing same | KOREA INST SCI & TECH | 2013-03-13 | — | — | CN | disclosed |