SCHEMBL27909554

SCHEMBL27909554

Oc1ccc(O)c(-c2ccc(I)cc2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.47
PELI1 Q96FA3 2/20 0.46
ALOX5 P09917 2/20 0.43
ESR2 Q92731 6/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
GFER P55789 1/20 0.41
RUNX1 Q01196 1/20 0.41
CBFB Q13951 1/20 0.41
NPC1 O15118 1/20 0.41
BACE1 P56817 1/20 0.39
HSD17B10 Q99714 1/20 0.38
ESR1 P03372 4/20 0.38
ABL1 P00519 1/20 0.38
ABCB1 P08183 1/20 0.38
BCR P11274 1/20 0.38
DYRK1A Q13627 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13861252 0.89 PELI1 (0.53) PELI1ALOX5ESR2ALDH1A1GAA
SCHEMBL2770537 0.86 PELI1 (0.57) PELI1ALOX5ESR2ALDH1A1GAA
SCHEMBL2345214 0.84 ALOX5 (0.61) MIFALOX5ESR2MAPTHSD17B10
SCHEMBL13867887 0.80 PELI1 (0.52) PELI1ALOX5ESR2ALDH1A1GAA
SCHEMBL29615176 0.78 BACE1 (0.56) MIFPELI1ALOX5ESR2BACE1
SCHEMBL9504663 0.78 ALOX5 (0.65) PELI1ALOX5ESR2ALDH1A1GAA
SCHEMBL6030259 0.78 PIM1 (0.54) MIFPELI1ALOX5ESR2GAA
SCHEMBL1163817 0.78 BACE1 (0.56) MIFPELI1ALOX5ESR2BACE1
SCHEMBL28005746 0.78 KMT2A (0.51) MIFPELI1ALOX5ESR2ALDH1A1
SCHEMBL11583585 0.78 ALDH1A1 (0.50) PELI1ALOX5ESR2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105461613-B Carbazole derivates grafted monomers, preparation method and its application in polyarylether polymer 吉林大学 2018-02-09 CN claimed
CN-105440279-B Polyarylether containing the hydrogen carbazole side base of 3,6 2 (triphenyl) methyl 9 and preparation method thereof 吉林大学 2017-06-09 CN claimed
CN-105461613-B Carbazole derivates grafted monomers, preparation method and its application in polyarylether polymer 吉林大学 2018-02-09 CN disclosed
CN-105440279-B Polyarylether containing the hydrogen carbazole side base of 3,6 2 (triphenyl) methyl 9 and preparation method thereof 吉林大学 2017-06-09 CN disclosed
CN-102942707-B Preparation method for perfluoro sulfonic side chain polyarylether proton exchange membrane UNIV JILIN 2015-02-11 CN disclosed
CN-102942707-A Preparation method for perfluoro sulfonic side chain polyarylether proton exchange membrane UNIV JILIN 2013-02-27 CN disclosed