SCHEMBL6030259

SCHEMBL6030259

Oc1ccc(O)c(-c2ccc(Cl)cc2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 2/20 0.54
ALOX5 P09917 3/20 0.54
MAPT P10636 4/20 0.51
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
CYP1A2 P05177 2/20 0.51
CYP3A4 P08684 2/20 0.51
CYP2D6 P10635 2/20 0.51
CYP2C9 P11712 2/20 0.51
ALOX15 P16050 2/20 0.51
ALOX12 P18054 2/20 0.51
CYP2C19 P33261 2/20 0.51
HSD17B10 Q99714 2/20 0.51
USP2 O75604 1/20 0.51
HTT P42858 2/20 0.47
NPSR1 Q6W5P4 2/20 0.47
GAA P10253 1/20 0.47
MAPK1 P28482 1/20 0.47
GPR55 Q9Y2T6 1/20 0.47
CA12 O43570 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13861252 0.89 PELI1 (0.53) ALOX5MAPTHSD17B10HTTGAA
SCHEMBL9441987 0.87 PIM1 (0.52) PIM1ALOX5MAPTKMT2AMEN1
SCHEMBL2770537 0.86 PELI1 (0.57) ALOX5MAPTHSD17B10HTTGAA
SCHEMBL6068151 0.84 MEN1 (0.62) PIM1ALOX5MAPTKMT2AMEN1
SCHEMBL9812827 0.84 ALOX5 (0.58) ALOX5MAPTKMT2AMEN1CYP1A2
SCHEMBL22891490 0.83 MAPT (0.62) PIM1ALOX5MAPTKMT2AMEN1
Methane SCHEMBL28101908 0.83 MEN1 (0.60) PIM1ALOX5MAPTKMT2AMEN1
Ethane SCHEMBL28177585 0.81 MEN1 (0.58) ALOX5MAPTKMT2AMEN1CYP1A2
SCHEMBL13867887 0.80 PELI1 (0.52) ALOX5MAPTHSD17B10HTTGAA
SCHEMBL28711970 0.80 MEN1 (0.51) PIM1ALOX5MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100366233-C Hair conditioning compositions and application in hair dye composition thereof PROCTER & GAMBLE (US) 2008-02-06 CN disclosed
US-6986886-B2 Hair conditioning compositions and their use in hair coloring compositions THE PROCTER & GAMBLE COMPANY (US) 2006-01-17 US disclosed
CN-1209094-C Hair coloring compositions and methods PROCTER & GAMBLE (US) 2005-07-06 CN disclosed
US-20040158941-A1 Hair colouring and conditioning compositions THE PROCTER & GAMBLE COMPANY (US) 2004-08-19 US disclosed
US-20040158938-A1 Method for colouring hair THE PROCTER & GAMBLE COMPANY 2004-08-19 US disclosed
US-6758866-B2 AQUEOUS SOLUTION OF CHELATE COMPOUND, OXIDATION COLOR DYE AND COUPLER UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-07-06 US disclosed
CN-1153562-C Hair coloring compositions ���޿��غ͸ʱ�����˾ 2004-06-16 CN disclosed
CN-1479606-A Hair conditioning composition and use thereof in hair dyeing compositions 宝洁公司 2004-03-03 CN disclosed
US-6695888-B2 COMPLEX TRANSITION METAL HAIR DYE UNILEVER HOME & PERSONAL CARE, USA, DIVISION OF CONOPCO, INC. 2004-02-24 US disclosed
WO-2004014328-A1 ONE STEP HAIR COLORING COMPOSITIONS COMPRISING WATER SOLUBLE CARBONATE RELEASING SALTS UNILEVER PLC (GB) 2004-02-19 WO disclosed
WO-1997024105-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed
WO-1997024107-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed
EP-0337175-B1 ELECTROCHEMICAL SYNTHESIS OF 2-ARYL-HYDROQUINONES MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1993-05-19 EP disclosed
US-5098531-A ELECTROCHEMICAL SYNTHESIS OF 2-ARYL-HYDROQUINONES ISTITUTO GUIDO DONEGANI S.P.A. (IT) 1992-03-24 US disclosed
EP-0337175-A1 Electrochemical synthesis of 2-aryl-hydroquinones MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1989-10-18 EP disclosed
EP-0032063-B1 NOVEL SUBSTITUTED ARYLENE COMPOUNDS AND PROCESSES FOR THEIR PRODUCTION WARNER-LAMBERT COMPANY (US) 1984-03-14 EP disclosed
US-4351950-A Anti-arteriosclerotic agents WARNER-LAMBERT COMPANY (US) 1982-09-28 US disclosed
EP-0032063-A2 Novel substituted arylene compounds and processes for their production WARNER-LAMBERT COMPANY (US) 1981-07-15 EP disclosed
US-4153779-A Liquid crystal copolyester containing a substituted phenylhydroquinone EASTMAN KODAK COMPANY (US) 1979-05-08 US disclosed
US-3957424-A Enzyme-activated oxidative process for coloring hair THE PROCTER & GAMBLE COMPANY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040158941-A1 Hair colouring and conditioning compositions FNIP1, CUTA, SHH PIM1 4784/4885ALOX5 1144/4885MAPT 2803/4885
US-20040158938-A1 Method for colouring hair COX5B, SHH, DNMT3A PIM1 4632/4885ALOX5 2331/4885MAPT 3941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.