Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27859616 | 0.85 | TDP1 (0.41) | TSHRSMN1; SMN2CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL27433629 | 0.82 | TSHR (0.44) | TSHRSMN1; SMN2CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL9618428 | 0.82 | LMNA (0.45) | TSHRSMN1; SMN2CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL3671321 | 0.80 | LMNA (0.46) | TSHRSMN1; SMN2CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL28155395 | 0.79 | LMNA (0.46) | TSHRSMN1; SMN2CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL27441320 | 0.77 | SMN1; SMN2 (0.43) | TSHRSMN1; SMN2CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL27972253 | 0.77 | CTSK (0.44) | SMN1; SMN2CYP3A4CYP1A2CYP2D6MEN1 | |
| SCHEMBL17894167 | 0.77 | ALDH1A1 (0.57) | TSHRCYP1A2MEN1CYP2C9CYP2C19 | |
| SCHEMBL3267939 | 0.76 | CETP (0.43) | SMN1; SMN2CYP3A4CYP1A2CYP2D6MEN1 | |
| SCHEMBL27440136 | 0.75 | LMNA (0.49) | TSHRSMN1; SMN2CYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103201271-A | Derivatives of oxadiazole and pyridazine, their preparation and their application in therapeutics | SANOFI SA | 2013-07-10 | — | — | CN | disclosed |