Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.53 |
| ▸ | FABP3 | P05413 | 3/20 | 0.52 |
| ▸ | FABP4 | P15090 | 3/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.51 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27516459 | 0.87 | TTR (0.59) | TSHRTTRFABP3FABP4NOTUM | |
| SCHEMBL28016199 | 0.75 | ALDH1A1 (0.55) | TSHRTTRNOTUMMYCALDH1A1 | |
| SCHEMBL27532000 | 0.74 | TTR (0.56) | TTRMYCPOLBALDH1A1KDM4E | |
| SCHEMBL28015624 | 0.73 | TTR (0.59) | TTRNOTUMMYCDHODH | |
| SCHEMBL27796585 | 0.73 | TTR (0.59) | TSHRTTRNOTUMMYCPOLB | |
| SCHEMBL28759892 | 0.73 | TTR (0.59) | TSHRTTRNOTUMMYCPOLB | |
| SCHEMBL27458636 | 0.73 | TTR (0.59) | TTRFABP3FABP4NOTUMALDH1A1 | |
| SCHEMBL8439147 | 0.73 | FABP3 (0.48) | TSHRFABP3FABP4ALDH1A1DHODH | |
| SCHEMBL27517441 | 0.73 | NPC1 (0.54) | TSHRTTRFABP3FABP4NOTUM | |
| SCHEMBL27922028 | 0.73 | KEAP1 (0.51) | TSHRALDH1A1KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103189363-B | Biaryl linked aryl triazolones and uses thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-07-29 | — | — | CN | disclosed |
| CN-103189363-A | Biaryl linked aryl triazolones and uses thereof | BAYER IP GMBH | 2013-07-03 | — | — | CN | disclosed |