Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27709822 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TP53TSHRCASP1SMN1; SMN2 | |
| SCHEMBL9558834 | 0.82 | TSHR (0.68) | ALDH1A1TP53TSHRCASP1SMN1; SMN2 | |
| SCHEMBL27390478 | 0.82 | CA1 (0.61) | ALDH1A1TP53TSHRCASP1SMN1; SMN2 | |
| SCHEMBL27516459 | 0.81 | TTR (0.59) | ALDH1A1TP53TSHRNOTUMAKR1C3 | |
| SCHEMBL28857634 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TP53TSHRCASP1SMN1; SMN2 | |
| SCHEMBL27517441 | 0.77 | NPC1 (0.54) | ALDH1A1TP53TSHRCASP1SMN1; SMN2 | |
| SCHEMBL28840070 | 0.77 | ALDH1A1 (0.55) | ALDH1A1TP53TSHRCASP1SMN1; SMN2 | |
| SCHEMBL11235643 | 0.76 | POLB (0.50) | ALDH1A1TP53TSHRCASP1SMN1; SMN2 | |
| SCHEMBL27909640 | 0.75 | TSHR (0.53) | ALDH1A1TSHRNOTUMAKR1C3AKR1C2 | |
| SCHEMBL28016213 | 0.75 | KDM4E (0.46) | ALDH1A1TP53NOTUMCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104672157-B | A kind of preparation method of aryltriazolinones | 山东潍坊润丰化工股份有限公司 | 2017-06-27 | — | — | CN | disclosed |
| CN-104672157-A | Method for preparing aryl triazolinone | SHANDONG WEIFANG RAINBOW CHEM | 2015-06-03 | — | — | CN | disclosed |