Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2442818 | 0.79 | LMNA (0.48) | LMNAHTTSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL2443799 | 0.78 | LMNA (0.47) | LMNAHTTSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL2441569 | 0.76 | MITF (0.47) | LMNAHTTSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL15686430 | 0.68 | ALDH1A1 (0.42) | LMNASMN1; SMN2SOS1ALDH1A1KDM4E | |
| Ethoxycarbonyl Group SCHEMBL27909768 | 0.67 | LMNA (0.44) | LMNAHTTSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL16324474 | 0.64 | ALDH1A1 (0.68) | LMNASMN1; SMN2CYP1A2POLBSOS1 | |
| SCHEMBL22619846 | 0.63 | ALDH1A1 (0.62) | LMNAHTTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL29941447 | 0.62 | LMNA (0.54) | LMNASMN1; SMN2POLBALDH1A1KMT2A | |
| SCHEMBL20591079 | 0.62 | ALDH1A1 (0.45) | LMNASMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28804438 | 0.62 | ALDH1A1 (0.42) | LMNAHTTSMN1; SMN2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103189363-A | Biaryl linked aryl triazolones and uses thereof | BAYER IP GMBH | 2013-07-03 | — | — | CN | disclosed |