Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 5/20 | 0.45 |
| ▸ | ARG2 | P78540 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11725592 | 0.96 | ARG1 (0.46) | ARG1ARG2MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL7327831 | 0.86 | PAOX (0.43) | SMN1; SMN2CYP1A2MAPTALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL27945156 | 0.82 | SIGMAR1 (0.46) | SMN1; SMN2MAPTALDH1A1POLBCHRM2 | |
| SCHEMBL15434608 | 0.82 | SMN1; SMN2 (0.56) | ARG1ARG2SMN1; SMN2MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL27945162 | 0.82 | SIGMAR1 (0.46) | SMN1; SMN2MAPTALDH1A1POLBCHRM2 | |
| SCHEMBL20527306 | 0.80 | KCNA3 (0.38) | ARG1ARG2POLBOPRM1KCNH2 | |
| SCHEMBL499877 | 0.78 | HTR2A (0.40) | MAPK1SMN1; SMN2CYP1A2MAPTALDH1A1 | |
| SCHEMBL11801318 | 0.77 | ARG1 (0.43) | ARG1ARG2MAPK1SMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL27966524 | 0.77 | ARG1 (0.50) | ARG1ARG2MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL3696273 | 0.77 | SMN1; SMN2 (0.41) | ARG1ARG2MAPK1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679287-B | Nicotinic acetylcholine receptor modulators | SIENA BIOTECH SPA | 2013-03-27 | — | — | CN | disclosed |